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孕期用药及其他暴露风险感知。

Perception of risk regarding the use of medications and other exposures during pregnancy.

机构信息

Department of Pharmacy, School of Pharmacy, University of Oslo, Oslo, Norway.

出版信息

Eur J Clin Pharmacol. 2010 Feb;66(2):207-14. doi: 10.1007/s00228-009-0744-2. Epub 2009 Oct 20.

Abstract

BACKGROUND

Perception of risk may impact a woman's decision to take a needed drug during pregnancy. There is a paucity of research on this topic in the literature.

OBJECTIVES

(1) To evaluate the perception of risk of 17 commonly used drugs and other substances by pregnant women. (2) To investigate which sources of information regarding exposures during pregnancy were most commonly used by women.

METHODS

A questionnaire was developed through the University of Oslo's website for Internet surveys and posted on four Web pages used by pregnant women and mothers, from mid-September 2008 through October 2008. The inclusion criteria included women who were (1) pregnant or 2) a mother of a child less than 5 years old.

RESULTS

A total of 1,793 eligible women completed the questionnaire. Most women overestimated the teratogenic risk associated with all the drugs during pregnancy. Characteristics of the women that were associated with a high perception of risk were primiparity, higher age, higher education, and choosing not to use a drug during pregnancy. More than 80% of the women had used drugs during pregnancy, mostly paracetamol, penicillins and reflux medications. The physician, the product information leaflet and the pharmacist were the three most frequently used sources of information.

CONCLUSION

Women overestimate the risk of drug use and other exposures during pregnancy. Therefore, it is important for health care providers to use evidence-based information, to reduce unnecessary anxiety, and to ensure safe and appropriate treatment during pregnancy.

摘要

背景

对风险的感知可能会影响女性在怀孕期间服用所需药物的决定。这一主题在文献中研究甚少。

目的

(1)评估孕妇对 17 种常用药物和其他物质的风险感知。(2)调查女性在怀孕期间最常使用哪些信息来源。

方法

通过奥斯陆大学的网站为互联网调查开发了一份问卷,并于 2008 年 9 月中旬至 10 月在四个供孕妇和母亲使用的网页上发布。纳入标准包括(1)孕妇或(2)5 岁以下儿童的母亲。

结果

共有 1793 名符合条件的女性完成了问卷。大多数女性高估了怀孕期间所有药物的致畸风险。与高风险感知相关的女性特征是初产妇、年龄较大、受教育程度较高以及怀孕期间选择不使用药物。超过 80%的女性在怀孕期间使用过药物,主要是扑热息痛、青霉素和反流药物。医生、药品说明书和药剂师是最常使用的三种信息来源。

结论

女性高估了怀孕期间药物使用和其他暴露的风险。因此,医疗保健提供者使用基于证据的信息非常重要,以减少不必要的焦虑,并确保怀孕期间的安全和适当治疗。

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