阿德尔亨德反应的机制：免疫学研究。一。
THE MECHANISM OF THE ABDERHALDEN REACTION : STUDIES ON IMMUNITY. I.
机构信息
Pathological and Research Laboratories of the Western Pennsylvania Hospital, Pittsburgh.
出版信息
J Exp Med. 1915 Mar 1;21(3):221-38. doi: 10.1084/jem.21.3.221.
Abstract
- The Abderhalden reaction is specific. 2. The properties of serum on which it depends develop in experimental animals simultaneously with antibodies during the process of immunization. 3. It is impossible to observe by direct methods the presence of digesting ferments in the blood of immune animals. 4. The Abderhalden test may be resolved into two phases. A dialyzable substance appears in the second phase and is the result of the autodigestion of serum. 5. The autodigestion of serum in the Abderhalden test is due to the removal of antitrypsin from the serum by the sensitized substratum.
摘要
阿狄森氏反应具有特异性。
该反应所依赖的血清性质，在免疫动物体内与抗体同时，通过实验产生。
用直接方法观察免疫动物血液中消化酶的存在是不可能的。
阿狄森氏试验可以分为两个阶段。在第二阶段出现可透析物质，是血清自动消化的结果。
阿狄森氏试验中血清的自动消化是由于敏感基质从血清中除去了抗胰蛋白酶。
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