肺炎球菌与抗肺炎球菌血清的酒精提取物之间发生的特定絮凝反应。
A SPECIFIC FLOCCULATION REACTION OCCURRING BETWEEN ALCOHOLIC EXTRACTS OF PNEUMOCOCCI AND ANTIPNEUMOCOCCUS SERUM.
机构信息
Division of Laboratories and Research, New York State Department of Health, Albany.
出版信息
J Exp Med. 1927 Jan 31;45(2):227-41. doi: 10.1084/jem.45.2.227.
Abstract
- A flocculation reaction has been described which occurs between alcoholic extracts of pneumococci and antipneumococcus serum. 2. The reaction appears to be species-specific. It is not strictly type-specific, as slight or moderate cross-reactions occurred between Type I serums and Type II and Type III extracts. 3. The flocculating power of the serum from five horses undergoing immunization with pneumococcus, Type I, did not develop to any extent before the end of the 4th or 5th month. 4. In the case of two of these horses in which it was possible to carry out parallel tests on a larger number of subsequent bleedings until the end of immunization, some relationship was suggested between the flocculating power and the protective titer as ascertained by the routine method of standardization in mice.
摘要
已描述了一种沉淀反应，它发生在肺炎球菌的酒精提取物和抗肺炎球菌血清之间。
该反应似乎具有种属特异性。它不是严格的血清型特异性，因为在 I 型血清和 II 型和 III 型提取物之间发生了轻微或中度的交叉反应。
用 I 型肺炎球菌免疫的五匹马的血清的絮凝能力在第 4 或第 5 个月结束之前没有任何程度的发展。
在其中两匹马的情况下，直到免疫结束，都可以对更多随后的采血进行平行测试，这表明在小鼠常规标准化方法确定的絮凝能力和保护效价之间存在一定的关系。
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