淋巴结的滤过功能。
THE FILTERING CAPACITY OF LYMPH NODES.
机构信息
Department of Physiology, The Harvard School of Public Health, and the Department of Bacteriology, The Harvard Medical School, Boston.
出版信息
J Exp Med. 1934 Mar 31;59(4):393-405. doi: 10.1084/jem.59.4.393.
In anesthetized dogs the popliteal lymph node alone, and the popliteal and iliac lymph nodes in series, have been perfused with solutions containing dog erythrocytes and streptococci. The perfusions have been carried out under conditions of lymph flow and pressure within the limits of those occurring in the actively moving dog, or after a severe degree of inflammatory swelling has developed. Figures for filtration are given, with protocols of typical experiments. They indicate that normal lymph nodes possess a high degree of filtering efficiency-an efficiency so great as to make it fairly certain that in a part kept at rest early in an infection, practically no microorganisms would escape the nodes in the line of drainage.
在麻醉犬中，单独的腘淋巴结，以及连续的腘淋巴结和髂淋巴结，已经用含有狗红细胞和链球菌的溶液进行了灌注。这些灌注是在淋巴流量和压力的条件下进行的，这些条件在活跃运动的狗中发生，或者在炎症肿胀已经发展到严重程度后发生。给出了过滤的数值，并提供了典型实验的方案。它们表明，正常的淋巴结具有高度的过滤效率——这种效率非常高，以至于可以相当肯定地说，在感染早期保持静止的一个部位，实际上没有微生物能够从引流线上的淋巴结中逃脱。
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