旋毛虫传播淋巴细胞脉络丛脑膜炎病毒。
THE TRANSMISSION OF THE VIRUS OF LYMPHOCYTIC CHORIOMENINGITIS BY TRICHINELLA SPIRALIS.
机构信息
Department of Bacteriology, University of Rochester, School of Medicine and Dentistry, Rochester, New York.
出版信息
J Exp Med. 1947 May 31;85(6):759-69. doi: 10.1084/jem.85.6.759.
In experiments in which guinea pigs were infected concurrently with the virus of lymphocytic choriomeningitis and the parasitic nematode, Trichinella spiralis, proof was obtained that trichinella larvae, after maturation in the muscles, had acquired the virus and were capable of transmitting it to new susceptible hosts. Transmission resulted both when living larvae were fed to normal guinea pigs and when triturated dead larvae were injected subcutaneously. Control experiments and other tests made plain that transmission of the virus was not due to mere adherence of it to the outer surface of the larvae but that these actually harbored it. The significance of these experiments in relation to natural transmission of the virus of lymphocytic choriomeningitis remains to be determined.
在同时感染淋巴细胞性脉络丛脑膜炎病毒和寄生虫旋毛虫的豚鼠实验中，证明了在肌肉中成熟的旋毛虫幼虫已经获得了病毒，并能够将其传播给新的易感宿主。当将活幼虫喂给正常豚鼠时，以及当将研磨死幼虫皮下注射时，都会导致传播。对照实验和其他测试清楚地表明，病毒的传播不是因为它仅仅附着在幼虫的外表面上，而是因为幼虫实际上携带了它。这些实验与淋巴细胞性脉络丛脑膜炎病毒的自然传播之间的关系还有待确定。
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