Department of Psychological Medicine and Psychiatry, King's College London, Weston Education Centre, London, UK.
Psychol Med. 2010 Aug;40(8):1269-79. doi: 10.1017/S003329170999153X. Epub 2009 Nov 6.
Only one previous randomized controlled trial (RCT) has examined the efficacy of cognitive behaviour therapy (CBT) for chronic fatigue syndrome (CFS) in children. The aim of this study was to compare family-focused CBT with psycho-education for CFS in adolescents.
Sixty-three 11- to 18-year-olds (43 girls, 20 boys) with CFS were randomly assigned to either family-focused CBT or psycho-education delivered over 6 months. School attendance was the main outcome, which was assessed at the end of treatment and at 3, 6 and 12 months follow-up.
At the main outcome point (the 6-month follow-up) both groups had improved similarly. However, although those who received family-focused CBT were attending school for longer than those who received psycho-education, at discharge from treatment and at 3 months follow-up, they improved less quickly across the follow-up period.
Adolescents with CFS get back to school more quickly after family-focused CBT. This is important as they are at a crucial stage of their development. However, the finding that psycho-education was as effective as family-focused CBT at 6 and 12 months follow-up has important implications for health service delivery.
仅有一项既往随机对照试验(RCT)研究了认知行为疗法(CBT)对儿童慢性疲劳综合征(CFS)的疗效。本研究旨在比较家庭为中心的 CBT 与心理教育对青少年 CFS 的疗效。
63 名 11-18 岁(43 名女孩,20 名男孩)的 CFS 患者被随机分配至家庭为中心的 CBT 或心理教育组,疗程为 6 个月。主要结局是在校出勤情况,在治疗结束时和 3、6、12 个月随访时进行评估。
在主要结局点(6 个月随访),两组的改善情况相似。然而,尽管接受家庭为中心的 CBT 的患者在校时间长于接受心理教育的患者,但在治疗结束和 3 个月随访时,他们在随访期间的改善速度较慢。
青少年 CFS 接受家庭为中心的 CBT 治疗后更快地返回学校。这很重要,因为他们正处于发展的关键阶段。然而,心理教育在 6 和 12 个月随访时与家庭为中心的 CBT 一样有效,这对医疗服务的提供具有重要意义。