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寻常型银屑病中医证候的分布与演变。

Distribution and development of the TCM syndromes in psoriasis vulgaris.

机构信息

Department of Dermatology and Venereology, Beijing TCM Hospital Affiliated to the Capital Medical University, Beijing 100010, China.

出版信息

J Tradit Chin Med. 2009 Sep;29(3):195-200. doi: 10.1016/s0254-6272(09)60064-9.

Abstract

OBJECTIVE

To study the distribution and development rules of the TCM syndromes in psoriasis vulgaris.

METHODS

Based on the clinical epidemiologic mass survey, the study was carried out by means of a status survey, multi-center and large-sample research. The data base was set up by EPIINFO6.0. The SPSS was used to do the statistical analyses in 2651 cases of psoriasis vulgaris to study the correlations among the distribution and development of the TCM syndromes, the stages of the disease, nationality, psoriasis history, family history, smoking history, alcohol drinking history, and severity of the disease.

RESULTS

The TCM syndromes in psoriasis vulgaris mainly include the blood-heat syndrome (53.8%), blood-dryness syndrome (27.4%), and blood-stasis syndrome (18.1%). Other syndromes were rarely seen, covering 0.6%. The concurrent syndromes mainly involve dampness, heat, blood stasis and toxin. The distribution differences of the main syndromes at different stages of the disease had statistical significance (P < 0.01). The syndrome distribution is not related with nationality and family history (P > 0.05), but it was closely related with the psoriasis history, smoking history, alcohol drinking history, and severity of the disease (P < 0.01).

CONCLUSION

At the initial stage, psoriasis vulgaris usually manifests itself as the blood-heat syndrome, and later it may be improved or turn into the blood-dryness or blood-stasis syndrome. Smoking, alcohol consumption, and severity of the disease may play a role in the syndrome's transformation.

摘要

目的

研究寻常型银屑病中医证候的分布及演变规律。

方法

采用临床流行病学大样本、多中心横断面调查方法,基于临床流行病学调查,运用 EPIINFO6.0 建立数据库,对 2651 例寻常型银屑病患者进行中医证候分布与疾病分期、民族、银屑病病史、家族史、吸烟史、饮酒史、病情严重度的相关性研究,采用 SPSS 软件进行统计学分析。

结果

寻常型银屑病中医证候主要包括血热证(53.8%)、血燥证(27.4%)和血瘀证(18.1%),兼夹证主要涉及湿、热、血瘀、毒邪,不同分期中医证候分布差异有统计学意义(P<0.01),与民族、家族史无关(P>0.05),与银屑病病史、吸烟史、饮酒史、病情严重度密切相关(P<0.01)。

结论

寻常型银屑病初发以血热证多见,随着病情的进展,可能向血燥证或血瘀证转化,吸烟、饮酒、病情严重度可能与证候转化有关。

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