大鼠营养转换期间肩胛间棕色脂肪组织在体内对葡萄糖的利用
Glucose utilization by interscapular brown adipose tissue in vivo during nutritional transitions in the rat.
作者信息
Holness M J, Liu Y L, Beech J S, Sugden M C
机构信息
Department of Biochemistry, Faculty of Basic Medical Sciences, Queen Mary and Westfield College, London, U.K.
出版信息
Biochem J. 1991 Jan 1;273(Pt 1)(Pt 1):233-5. doi: 10.1042/bj2730233.
Abstract
Glucose utilization indices (GUI) of interscapular brown adipose tissue (IBAT) declined by 84% after 48 h starvation. Two-thirds of the overall response was observed within 6 h, correlating with decreased insulin concentrations. Re-feeding 48 h-starved rats restored insulin concentrations and evoked a rapid 15-fold increase in IBAT GUI. GUI values after re-feeding were markedly higher than those observed at equivalent insulin concentrations in control post-absorptive rats.
摘要
饥饿48小时后，肩胛间棕色脂肪组织（IBAT）的葡萄糖利用指数（GUI）下降了84%。在6小时内观察到了整体反应的三分之二，这与胰岛素浓度降低相关。对饥饿48小时的大鼠重新喂食可恢复胰岛素浓度，并使IBAT的GUI迅速增加15倍。重新喂食后的GUI值明显高于吸收后对照大鼠在同等胰岛素浓度下观察到的值。
相似文献
1
Glucose utilization by interscapular brown adipose tissue in vivo during nutritional transitions in the rat.
Biochem J. 1991 Jan 1;273(Pt 1)(Pt 1):233-5. doi: 10.1042/bj2730233.
2
Glucose transporter expression and glucose utilization in skeletal muscle and brown adipose tissue during starvation and re-feeding.
Biochem J. 1992 Feb 15;282 ( Pt 1)(Pt 1):231-5. doi: 10.1042/bj2820231.
3
Physiological modulation of the uptake and fate of glucose in brown adipose tissue.
Biochem J. 1993 Oct 1;295 ( Pt 1)(Pt 1):171-6. doi: 10.1042/bj2950171.
4
Effect of 36-hour starvation on in vivo amino acid and glucose uptake by rat brown adipose tissue.
Biochem Int. 1989 May;18(5):895-902.
5
The impact of increased dietary lipid on the regulation of glucose uptake and oxidation by insulin in brown- and a range of white-adipose-tissue depots in vivo.
Int J Obes Relat Metab Disord. 1999 Jun;23(6):629-38. doi: 10.1038/sj.ijo.0800892.
6
Effects of dichloroacetate on fatty acid synthesis in interscapular brown adipose tissue of the rat in vivo and in vitro.
Horm Metab Res. 1983 Oct;15(10):482-5. doi: 10.1055/s-2007-1018764.
7
Brown-adipose-tissue lipogenesis in starvation: effects of insulin and (-) hydroxycitrate.
Biosci Rep. 1982 May;2(5):289-97. doi: 10.1007/BF01115114.
8
In vitro alanine utilization by rat interscapular brown adipose tissue.
Biochim Biophys Acta. 1990 Oct 12;1036(1):6-10. doi: 10.1016/0304-4165(90)90206-c.
9
Interactions between insulin and thyroid hormone in the control of lipogenesis.
Biochem J. 1983 Mar 15;210(3):937-44. doi: 10.1042/bj2100937.
10
Glucose disposal by skeletal muscle in response to re-feeding after progressive starvation.
Biochem J. 1991 Jul 15;277 ( Pt 2)(Pt 2):429-33. doi: 10.1042/bj2770429.
引用本文的文献
1
Effects of burn injury, cold stress and cutaneous wound injury on the morphology and energy metabolism of murine brown adipose tissue (BAT) in vivo.
Life Sci. 2011 Jul 18;89(3-4):78-85. doi: 10.1016/j.lfs.2011.04.014. Epub 2011 May 4.
2
Metabolic response to glucose overload in surgical stress: energy disposal in brown adipose tissue.
Surg Today. 1996;26(3):151-7. doi: 10.1007/BF00311498.
3
Changes in lipoprotein lipase activities in adipose tissue, heart and skeletal muscle during continuous or interrupted feeding.
Biochem J. 1993 May 15;292 ( Pt 1)(Pt 1):113-9. doi: 10.1042/bj2920113.
4
Physiological modulation of the uptake and fate of glucose in brown adipose tissue.
Biochem J. 1993 Oct 1;295 ( Pt 1)(Pt 1):171-6. doi: 10.1042/bj2950171.
5
Glucose disposal by skeletal muscle in response to re-feeding after progressive starvation.
Biochem J. 1991 Jul 15;277 ( Pt 2)(Pt 2):429-33. doi: 10.1042/bj2770429.
6
Glucose transporter expression and glucose utilization in skeletal muscle and brown adipose tissue during starvation and re-feeding.
Biochem J. 1992 Feb 15;282 ( Pt 1)(Pt 1):231-5. doi: 10.1042/bj2820231.
本文引用的文献
1
Sympathetic and thyroid influences on metabolic rate in fed, fasted, and refed rats.
Am J Physiol. 1982 Sep;243(3):R339-46. doi: 10.1152/ajpregu.1982.243.3.R339.
2
Regional blood flow in rats after a single low-protein, high-carbohydrate test meal.
Am J Physiol. 1984 Jul;247(1 Pt 2):R160-6. doi: 10.1152/ajpregu.1984.247.1.R160.
3
The maximum capacity of glycolysis in brown adipose tissue and its relationship to control of the blood glucose concentration.
FEBS Lett. 1982 Nov 8;148(2):198-200. doi: 10.1016/0014-5793(82)80807-7.
4
5
A method to quantify glucose utilization in vivo in skeletal muscle and white adipose tissue of the anaesthetized rat.
Biochem J. 1985 May 15;228(1):103-10. doi: 10.1042/bj2280103.
6
Muscle glucose metabolism in exercising rats: comparison with insulin stimulation.
Am J Physiol. 1985 May;248(5 Pt 1):E575-80. doi: 10.1152/ajpendo.1985.248.5.E575.
7
Norepinephrine turnover in brown adipose tissue is stimulated by a single meal.
Am J Physiol. 1986 Jul;251(1 Pt 2):R13-7. doi: 10.1152/ajpregu.1986.251.1.R13.
8
Effects of fasting on tissue glucose utilization in conscious resting rats. Major glucose-sparing effect in working muscles.
Biochem J. 1987 Aug 15;246(1):241-4. doi: 10.1042/bj2460241.
9
Fat feeding causes widespread in vivo insulin resistance, decreased energy expenditure, and obesity in rats.
Am J Physiol. 1986 Nov;251(5 Pt 1):E576-83. doi: 10.1152/ajpendo.1986.251.5.E576.
10
Glucose utilization in vivo and insulin-sensitivity of rat brown adipose tissue in various physiological and pathological conditions.
Biochem J. 1986 Jan 1;233(1):249-52. doi: 10.1042/bj2330249.
Zotero 插件