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胸骨深部伤口感染的经济学方面。

Economic aspects of deep sternal wound infections.

机构信息

Institute for Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Carl-Neuberg-Str. 1, D-30625 Hannover, Germany.

出版信息

Eur J Cardiothorac Surg. 2010 Apr;37(4):893-6. doi: 10.1016/j.ejcts.2009.10.005. Epub 2009 Nov 6.

Abstract

OBJECTIVES

Surgical-site infections are a very expensive complication in cardiac surgery. Thus, the total costs for coronary artery bypass grafting (CABG) surgery may substantially increase when a deep sternal wound infection (DSWI) occurs. This may be due to an extended length of stay (LOS), the need for additional surgical procedures, vacuum-assisted wound dressing and antibiotic therapy. This study compares the LOS in the hospital and on an intensive care unit (ICU) as well as the total costs for patients undergoing CABG depending upon the occurrence of a subsequent DSWI.

METHODS

A case-control study was performed. Total costs of DSWI cases were analysed and compared to patients undergoing CABG without DSWI. Inclusion criterion for cases was the development of a DSWI according to the CDC criteria during hospital stay after CABG. Two control patients without any signs or symptoms of an infection during hospital stay were matched to each case by (1) type of surgery according to their diagnosis-related group (DRG), (2) age +/-5 years, (3) gender and (4) duration of preoperative hospital stay +/-2 days, but at least as long as the time at risk of cases before infection.

RESULTS

Between January 2006 and March 2008, 17 CABG patients with DSWI (cases) and 34 matched controls were included. The median overall costs of a CABG case were 36,261 Euro compared with 13,356 Euro per control patient without infection (p<0.0001). The median overall LOS was 34.4 days versus 16.5 days, respectively (p=0.0006). The median LOS on ICU was 6.3 days versus 5.3 days (no significant difference).

CONCLUSION

DSWI represents an important economic factor for the hospital as they may almost triple the costs for patients undergoing CABG. Thus, appropriate infection control measures for the prevention of DSWI should be enforced.

摘要

目的

心脏手术后,手术部位感染是一种非常昂贵的并发症。因此,当发生深部胸骨伤口感染(DSWI)时,冠状动脉旁路移植术(CABG)的总费用可能会大幅增加。这可能是由于住院时间延长、需要额外的手术、真空辅助伤口敷料和抗生素治疗。本研究比较了发生 DSWI 后 CABG 患者的住院时间和重症监护病房(ICU)时间以及总费用。

方法

进行了病例对照研究。分析了 DSWI 病例的总费用,并与未发生 DSWI 的 CABG 患者进行了比较。病例的纳入标准是在 CABG 后住院期间根据 CDC 标准发生 DSWI。每个病例匹配了 2 名无感染迹象或症状的对照患者,匹配条件为:(1)按诊断相关组(DRG)进行手术类型;(2)年龄+/-5 岁;(3)性别;(4)术前住院时间+/-2 天,但至少与病例感染前的风险时间一样长。

结果

2006 年 1 月至 2008 年 3 月,共纳入 17 例 CABG 术后 DSWI 患者(病例)和 34 例匹配对照。每例 CABG 病例的总费用中位数为 36261 欧元,而无感染对照患者的费用中位数为 13356 欧元(p<0.0001)。总住院时间中位数分别为 34.4 天和 16.5 天(p=0.0006)。ICU 住院时间中位数分别为 6.3 天和 5.3 天(无显著差异)。

结论

DSWI 是医院的一个重要经济因素,因为它可能使 CABG 患者的费用增加近两倍。因此,应采取适当的感染控制措施预防 DSWI。

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