Das Amitav, Manickam P, Hutin Yvan, Pal B B, Chhotray G P, Kar S K, Gupte M D
National Institute of Epidemiology (ICMR), Chennai, Tamil Nadu, India.
J Health Popul Nutr. 2009 Oct;27(5):646-51. doi: 10.3329/jhpn.v27i5.3641.
In November 2003, an outbreak (41 cases; attack rate-4.3%; no deaths) of severe diarrhoea was reported from a village in Orissa, eastern India. Thirteen of these cases were hospitalized. A matched case-control study was conducted to identify the possible exposure variables. Since all wells were heavily chlorinated immediately after the outbreak, water samples were not tested. The cases were managed symptomatically. Descriptive epidemiology suggested clustering of cases around one public well. Vibrio cholerae El Tor O1, serotype Ogawa was isolated from four of six rectal swabs. The water from the public well was associated with the outbreak (matched odds ratio: 12; 95% confidence interval 1.2-44.1). On the basis of these conclusions, access to the well was barred immediately, and it was protected. This investigation highlighted the broader use of field epidemiology methods to implement public-health actions guided by epidemiologic data to control a cholera epidemic.
2003年11月,印度东部奥里萨邦的一个村庄报告了一起严重腹泻疫情(41例;发病率为4.3%;无死亡病例)。其中13例患者住院治疗。开展了一项配对病例对照研究以确定可能的暴露变量。由于疫情爆发后所有水井都立即进行了大量氯化处理,因此未对水样进行检测。对病例进行了对症治疗。描述性流行病学表明病例集中在一口公共水井周围。从六份直肠拭子中的四份分离出霍乱弧菌埃尔托生物型O1,小川血清型。公共水井的水与此次疫情有关(配对比值比:12;95%置信区间1.2 - 44.1)。基于这些结论,立即禁止使用该水井,并对其进行了保护。这项调查强调了更广泛地运用现场流行病学方法,以实施由流行病学数据指导的公共卫生行动来控制霍乱疫情。