Candiani G B, Fedele L, Vercellini P, Bianchi S, Di Nola G
First Department of Obstetrics and Gynecology, University of Milan, Italy.
Obstet Gynecol. 1991 Mar;77(3):421-4.
We evaluated the recovery of fertility and the relief of pain symptoms in a long-term follow-up of 42 women undergoing repetitive conservative surgery for recurrent endometriosis. The mean age of the patients was 31.1 +/- 4.3 years. At the time of their second operation the disease was stage IV in 14 women, stage III in 25, and stage I in three. After reoperation, the patients were followed for a mean period of 41.8 +/- 30.3 months. Pain symptoms returned in eight women, dysmenorrhea and deep dyspareunia in eight, and pelvic pain in seven. Eight of the 28 women (28.6%) who attempted to conceive achieved a total of 13 pregnancies. The corrected pregnancy rate was 35%, and the cumulative rate at 27 months was 30.7%. A third operation was necessary in six women after a mean period of 35 months. Conservative surgery is an effective therapeutic option for infertile patients with recurrent endometriosis.
我们对42例因复发性子宫内膜异位症而接受重复性保守手术的女性进行了长期随访，评估其生育能力的恢复情况和疼痛症状的缓解情况。患者的平均年龄为31.1±4.3岁。在她们第二次手术时，14例女性疾病处于IV期，25例处于III期，3例处于I期。再次手术后，对患者进行了平均41.8±30.3个月的随访。8例女性疼痛症状复发，其中8例痛经和深部性交痛复发，7例盆腔疼痛复发。28例尝试受孕的女性中有8例（28.6%）共怀孕13次。校正后的妊娠率为35%，27个月时的累积妊娠率为30.7%。平均35个月后，6例女性需要进行第三次手术。保守手术是复发性子宫内膜异位症不孕患者的一种有效治疗选择。
