Orzińska Agnieszka, Guz Katarzyna, Brojer Ewa
Zakład immunologii Hematologicznej i Transfuzjologicznej, Instytut Hematologii i Transfuzjologii w Warszawie.
Ginekol Pol. 2009 Oct;80(10):768-71.
The principles and results of noninvasive prenatal diagnosis in serological conflicts in Poland were described in the following work. Noninvasive fetal genotyping from plasma of immunized mother identifies women carrying fetus without incompatible antigen and risk of hemolytic disease. The presence of fetal RHD gene or RHCEc/E alleles in maternal plasma is examined routinely in Institute of Hematology and Blood Transfusion in Warsaw. Preliminary results of successful fetal KEL1 genotyping from maternal blood were obtained.
以下工作描述了波兰血清学冲突中非侵入性产前诊断的原理和结果。从免疫母亲的血浆中进行非侵入性胎儿基因分型可识别携带无不相容抗原胎儿的女性以及溶血病风险。华沙血液学和输血研究所常规检测母体血浆中胎儿RHD基因或RHCEc/E等位基因的存在。已获得从母体血液中成功进行胎儿KEL1基因分型的初步结果。