Department of Orthopaedic Surgery, University of Auckland, Auckland, New Zealand.
Int Orthop. 2010 Aug;34(6):783-7. doi: 10.1007/s00264-009-0884-0. Epub 2009 Nov 28.
We measured bone density (BD) changes to assess adaptive bone remodelling five years after uncemented total hip arthroplasty with taper-design femoral component using quantitative computed-tomography-assisted osteodensitometry (qCT). Nineteen consecutive patients (21 hips) with degenerative joint disease were enrolled in the study. A press-fit cup and a tapered uncemented stem ceramic-ceramic pairing were used in all patients. Serial clinical, radiological and qCT osteodensitometry assessments were performed after the index operation and at the one, two and five year follow-ups. At the latest follow-up, the clinical outcome was rated satisfactory in all hips. The radiological assessment showed signs of osteointegration with stable fixation of all cups and stems. Overall, there was evidence of a BD loss at year five (p = 0.004). We estimate that BD loss was between 2.2% and 12.1% in comparison with baseline postoperative values. Progressive loss of BD in the metaphyseal region was observed in all hips. We found unremarkable BD changes of diaphyseal cortical BD throughout the five year follow-up period. qCT osteodensitometry technology allows differentiation of cortical and cancellous BD changes over time. Periprosthetic BD changes at the five year follow-up are suggestive of stable stem osteointegration with proximal femoral diaphysis load transfer and metaphyseal stress shielding.
我们使用定量计算机断层扫描辅助骨密度测量(qCT)评估了五年后未使用水泥的锥形设计股骨组件全髋关节置换术后的骨密度(BD)变化,以评估适应性骨重塑。研究纳入了 19 例(21 髋)退行性关节病患者。所有患者均使用压配杯和锥形非水泥固定陶瓷-陶瓷配对。在指数手术后和 1、2、5 年随访时进行了连续的临床、放射学和 qCT 骨密度评估。在最近的随访中,所有髋关节的临床结果均评为满意。放射学评估显示所有髋臼和柄均有骨整合迹象,固定稳定。总的来说,第五年有证据表明 BD 丢失(p = 0.004)。我们估计与术后基线值相比,BD 丢失在 2.2%至 12.1%之间。所有髋关节的近段骨均观察到 BD 进行性丢失。我们发现整个五年随访期间骨干皮质 BD 的 BD 变化无明显变化。qCT 骨密度测量技术允许区分皮质和松质 BD 的随时间变化。五年随访时的假体周围 BD 变化提示近端股骨骨干负荷传递和近段骨应力屏蔽的稳定柄骨整合。