Department of Neuroscience, Uppsala University, Sweden.
Br J Ophthalmol. 2010 Sep;94(9):1136-9. doi: 10.1136/bjo.2009.170704. Epub 2009 Nov 30.
To study various aspects of treatment for retinopathy of prematurity (ROP) in a Swedish population of extremely preterm infants born before 27 weeks of gestation.
A national, prospective and population-based study was performed in Sweden from 1 April 2004 to 31 March 2007. The criteria for the treatment of ROP accorded with the recommendations of the Early Treatment for Retinopathy of Prematurity Cooperative Group.
Twenty per cent of the infants (99/506) were treated for ROP. The likelihood of reaching treatment criteria nearly doubled for each week of reduction in gestational age at birth. The first treatment was performed at an earlier postmenstrual age in the most immature infants. One third of the infants had more than one session of laser treatment.
A high percentage of these extremely preterm infants required treatment for ROP. The likelihood of reaching treatment criteria increased with a decline in gestational age at birth. Although only a few infants progressed to ROP stages 4 and 5, the findings of this study indicate a potential for improvement in the treatment routines, both regarding the timing and number of laser spots at the first treatment.
研究 27 周以下胎龄极早产儿中瑞典人群视网膜病变（ROP）的各种治疗方法。
2004 年 4 月 1 日至 2007 年 3 月 31 日，在瑞典进行了一项全国性、前瞻性、基于人群的研究。ROP 的治疗标准符合早产儿视网膜病变早期治疗合作组的建议。
20%的婴儿（99/506）接受了 ROP 治疗。出生时胎龄每减少一周，达到治疗标准的可能性几乎增加一倍。最不成熟的婴儿接受治疗的胎龄更早。三分之一的婴儿接受了不止一次的激光治疗。
这些极低出生体重儿中，有很大一部分需要接受 ROP 治疗。达到治疗标准的可能性随着出生时胎龄的下降而增加。尽管只有少数婴儿进展到 ROP 4 期和 5 期，但本研究的结果表明，治疗方案在首次治疗时的时机和激光点数量方面都有改进的潜力。
