Olezac A-S, Papanikolaou I, Bengrine-Lefevre L, Chouaid C
Service de Pneumologie, Hôpital Saint-Antoine, Paris, France.
Rev Mal Respir. 2009 Sep;26(7):769-72. doi: 10.1016/s0761-8425(09)72428-3.
Choriocarcinoma is a rare tumour which results from the anarchic proliferation of a gonadic or extra gonadic germinal cell.
A 45 year old pre menopausal woman of African origin presented with a persistent cough and deterioration of general status. The chest X-ray revealed a cavitated mass of the right upper lobe. Other lesions were associated (liver, kidney and scalp). Choriocarcinoma, suspected in the presence of an elevated ssHCG without a gravid uterus, was confirmed by biopsy excision of a haemorrhagic cutaneous lesion of the scalp. Despite the poor prognosis methotrexate based chemotherapy resulted in control of the disease and a good remission.
绒毛膜癌是一种罕见的肿瘤,由性腺或性腺外生殖细胞的无节制增殖引起。
一名45岁绝经前非洲裔女性,出现持续咳嗽和全身状况恶化。胸部X线显示右上叶有空洞性肿块。还伴有其他病变(肝脏、肾脏和头皮)。在血清人绒毛膜促性腺激素(β-hCG)升高且无妊娠子宫的情况下怀疑为绒毛膜癌,经头皮出血性皮肤病变活检切除确诊。尽管预后不良,但基于甲氨蝶呤的化疗使疾病得到控制并实现了良好缓解。