运动与呼吸道病毒感染。
Exercise and respiratory tract viral infections.
机构信息
Department of Kinesiology and Community Health, University of Illinois, Urbana-Champaign, USA.
出版信息
Exerc Sport Sci Rev. 2009 Oct;37(4):157-64. doi: 10.1097/JES.0b013e3181b7b57b.
Abstract
Prolonged intense exercise causes immunosuppression, whereas moderate-intensity exercise improves immune function and potentially reduces risk and severity of respiratory viral infections. Here, based on available evidence, we present a model whereby moderate exercise-induced increases in stress hormones reduce excessive local inflammation and skew the immune response away from a TH1 and toward a TH2 phenotype, thus improving outcomes after respiratory viral infections.
摘要
长时间剧烈运动可导致免疫抑制，而中等强度的运动可改善免疫功能，降低呼吸道病毒感染的风险和严重程度。在此，我们基于现有证据提出一个模型，即中等强度运动引起的应激激素增加可减少局部过度炎症，并使免疫反应从 TH1 向 TH2 表型倾斜，从而改善呼吸道病毒感染后的结果。
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