涂覆在金纳米新月阵列上的薄膜pH敏感水凝胶的近红外光学响应。

Near-infrared optical response of thin film pH-sensitive hydrogel coated on a gold nanocrescent array.

作者信息

Jiang Hao, Markowski Jan, Sabarinathan Jayshri

机构信息

Department of Electrical and Computer Engineering, the University of Western Ontario, London, Ontario, Canada.

出版信息

Opt Express. 2009 Nov 23;17(24):21802-7. doi: 10.1364/OE.17.021802.

DOI:10.1364/OE.17.021802

PMID:19997424

Abstract

A hydrogel-based chemiresponsive sensor for monitoring H(+) (pH) has been developed by coating the surface of a gold nanocrescent array structure with a thin film of a poly(2-hydroxylethyl methacrylate)-based (poly-HEMA) hydrogel. The transmission measurement results of the close-packed gold nanocrescent array fabricated via electron beam lithography demonstrate near-infrared localized surface plasmon resonance peaks with sensitivities up to 332 nm/RIU in detecting refractive index change. Measurements of the hydrogel under solutions of increasing pH show the plasmon peak blueshifts by 17 nm and the integrated transmission increases by 1.8 in the operating range of 4.5 - 6.4 pH, which is ideal for biochemical sensor applications.

摘要

通过用基于聚（甲基丙烯酸 2 - 羟乙酯）（聚 - HEMA）水凝胶的薄膜涂覆金纳米月牙阵列结构的表面，开发了一种用于监测 H⁺（pH）的基于水凝胶的化学响应传感器。通过电子束光刻制造的紧密堆积金纳米月牙阵列的透射测量结果表明，在检测折射率变化时，近红外局域表面等离子体共振峰的灵敏度高达 332 nm/RIU。在 pH 值不断增加的溶液中对水凝胶进行测量，结果表明在 4.5 - 6.4 的 pH 操作范围内，等离子体峰蓝移 17 nm，积分透射率增加 1.8，这对于生化传感器应用来说是理想的。