Department of Rectal Cancer Surgery, State Research Center of Coloproctology, Salyam Adyl st. 2, 123423, Moscow, Russia.
Tech Coloproctol. 2010 Mar;14(1):19-23. doi: 10.1007/s10151-009-0550-y. Epub 2009 Dec 15.
Loop ileostomy is widely employed as a defunctioning procedure for left-sided colonic anastomoses. Closure of the stoma carries a risk of morbidity and even mortality. The aim of this prospective trial was to evaluate the ability of stapled stoma closure to decrease the rates of perioperative morbidity.
One hundred and nineteen patients (mean age 56.2 +/- 5.4 years) underwent two-stage operations for rectal carcinoma with protective loop ileostomy between 2005 and 2008. All patients were randomly divided into two groups: 56 patients had conventional ileostomy takedown, while in the other 63, a functional end-to-end anastomosis was created using a linear stapler. Groups were comparable in terms of age, gender, body mass index, and other parameters.
Mean time of stoma closure using functional end-to-end anastomosis was 68 +/- 7, when compared to 92 +/- 11 min (P = 0.01) for conventional stoma closure. The overall morbidity rate after ileostomy closure using a stapler was 3.2%: one patient (1.6%) developed a wound infection and self-limited bleeding from the anastomotic line, while another patient (1.6%) had an ileal obstruction caused by adhesions and required additional intervention. Conventional ileostomy closure resulted in a 14.3% morbidity rate: six patients (10.7%) had prolonged ileus, 2 (3.6%) had small bowel obstruction, and 2 (3.6%) had wound infections (P = 0.04).
Functional end-to-end anastomosis reduces operating time and morbidity compared to conventional ileostomy takedown.
环式回肠造口术被广泛用作左侧结肠吻合的功能性手术。关闭造口存在发病甚至死亡的风险。本前瞻性试验旨在评估吻合器吻合术关闭造口术减少围手术期发病率的能力。
119 例(平均年龄 56.2±5.4 岁)患者在 2005 年至 2008 年间接受直肠肿瘤的两阶段手术,同时进行保护性环式回肠造口术。所有患者随机分为两组:56 例患者接受传统的回肠造口切除术,而在另外 63 例患者中,使用线性吻合器创建功能性端端吻合术。两组在年龄、性别、体重指数和其他参数方面具有可比性。
使用功能性端端吻合术关闭造口的平均时间为 68±7 分钟,而传统造口关闭的平均时间为 92±11 分钟(P=0.01)。使用吻合器关闭回肠造口后的总体发病率为 3.2%:1 例(1.6%)患者发生伤口感染和吻合线自限性出血,另 1 例(1.6%)患者发生粘连引起的回肠梗阻,需要进一步干预。传统的回肠造口关闭术导致 14.3%的发病率:6 例(10.7%)患者出现迁延性肠梗阻,2 例(3.6%)患者出现小肠梗阻,2 例(3.6%)患者出现伤口感染(P=0.04)。
与传统的回肠造口切除术相比,功能性端端吻合术可减少手术时间和发病率。