血浆 sRAGE 与 2 型糖尿病无冠心病患者高敏 C 反应蛋白独立相关。
Plasma sRAGE is independently associated with high sensitivity C-reactive protein in type 2 diabetes without coronary artery disease.
机构信息
The Department of Endocrinology, Jiangsu Province Hospital of TCM, 155 Han-Zhong Road, Nanjing 210029, China.
出版信息
Diabetes Res Clin Pract. 2010 Mar;87(3):e19-22. doi: 10.1016/j.diabres.2009.12.005. Epub 2009 Dec 23.
Abstract
Our studies suggest that plasma soluble advanced glycation end products (sRAGEs) has significantly negative association with high sensitivity C-reactive protein (hs-CRP) in 245 type 2 diabetes patients without diagnosed coronary artery disease (CAD). sRAGE maybe act as a novel biomarker for predicting the atherosclerosis in diabetes at the early stage.
摘要
我们的研究表明，在 245 例无诊断为冠心病（CAD）的 2 型糖尿病患者中，血浆可溶性晚期糖基化终产物（sRAGE）与高敏 C 反应蛋白（hs-CRP）呈显著负相关。sRAGE 可能是一种预测糖尿病早期动脉粥样硬化的新型生物标志物。
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