从蓝花棘豆中分离得到的单萜吲哚类葡萄糖生物碱和环烯醚萜苷。

Monoterpenoid glucoindole alkaloids and iridoids from Pterocephalus pinardii.

机构信息

Department of Chemistry, Faculty of Science, Ege University, Bornova, 35100 Izmir, Turkey.

出版信息

Magn Reson Chem. 2010 Mar;48(3):239-43. doi: 10.1002/mrc.2559.

PMID:20049748

Abstract

A new secondary metabolite, pterocephaline, along with the known cantleyoside, 7alpha-morroniside, 3beta,5alpha-tetrahydrodesoxycordifoline lactam, 5S-5-carboxyvincoside, sweroside, and loganin have been isolated from the aerial parts of P. pinardii (Dipsacaceae). Moreover, cantleyoside-methyl-hemiacetal and cantleyoside-dimethyl-acetal were obtained as seco-iridoid artifacts. The structures were elucidated by extensive spectroscopic methods including 1D-((1)H, (13)C and TOCSY) and 2D-NMR (DQF-COSY, HSQC and HMBC). Monoterpenoid glucoindole alkaloids were encountered for the first time in Dipsacaceae family.

摘要

从川续断科植物蓝花佩兰（Pterocephalus pinardii）的地上部分分离得到了一个新的次生代谢产物 pterocephaline 以及已知的 cantleyoside、7alpha-morroniside、3beta,5alpha-tetrahydrodesoxycordifoline lactam、5S-5-carboxyvincoside、sweroside 和 loganin。此外，还获得了 cantleyoside-methyl-hemiacetal 和 cantleyoside-dimethyl-acetal 作为 secoiridoid 人工制品。通过广泛的光谱方法，包括 1D-((1)H、(13)C 和 TOCSY)和 2D-NMR (DQF-COSY、HSQC 和 HMBC)，阐明了这些结构。在川续断科中首次遇到了单萜葡萄糖吲哚生物碱。