由于合并性 casts 肾病、淀粉样变性和轻链沉积病导致的肾衰竭。
Renal failure due to combined cast nephropathy, amyloidosis and light-chain deposition disease.
机构信息
Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA.
出版信息
Nephrol Dial Transplant. 2010 Apr;25(4):1340-3. doi: 10.1093/ndt/gfp735. Epub 2010 Jan 8.
PMID:20061318
Abstract
Renal dysfunction commonly occurs in multiple myeloma (MM) and is caused by deposition of abnormal light chain within various compartments of the kidney. Renal pathologic findings are diverse and include cast nephropathy (CN), amyloidosis and light-chain deposition disease (LCDD). We report a case of renal failure in a patient with MM caused by concurrent CN, amyloidosis and LCDD which has not been previously described.
摘要
肾功能障碍在多发性骨髓瘤（MM）中较为常见，是由异常轻链在肾脏各个部位沉积引起的。肾脏病理表现多样，包括管型肾病（CN）、淀粉样变性和轻链沉积病（LCDD）。我们报告了一例由 CN、淀粉样变性和 LCDD 同时引起的 MM 患者肾衰竭病例，此前尚未有相关报道。
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