Hsairi M, Dridi Y, Ben Abdallah M, Boussen H, Ben Hamida A
Institut Salah Azaiez.
Tunis Med. 2009 Jul;87(7):484-8.
Breast cancer is the principle cancer among female cancer in Tunisia. It represents 30% of the woman's cancers with about 1000 new cases per year. The main intervention control is mass screening using mammography in to reduce breast cancer mortality. Breast cancer screening efficacy in term of breast cancer mortality reduction is closely related to incidence and survival of this cancer. National Office of Family and Population (ONFP) conducted a pilot experience of breast cancer mass screening using the mammography in place. The main objective of this study is to calculate the potential number of life years saved through this pilot experience of the ONFP. For the methodology, we used the software Dismod (Disease Model) for the evaluation of the prevalence and the duration of the cancer of the breast in the governorate, as well as to estimate the number of life years saved. The potential breast cancer mortality reduction is 30% for women aged of 50 at 69 years, and 10% for those aged of 40 at 49 years. Breast cancer incidence in Ariana according to age for the period 1995-1998, has been calculated from the data base of cancer registry of the North of Tunisia. According to Dismod, mean duration in the absence of screening, is 11.12 years for the age group 40 to 49 years and 9.57 for the age group 50 at 69 years. Screening would increase these duration means of 2.22 years and 1.71 years, respectively for age groups 40 to 49 years and 50 at 69 years. The number of life years saved for 1000 women is of 2.97 years. In conclusion breast cancer screening using mammography would be actually little benefit in Tunisia. Mammography should be reserved for the diagnosis of the suspected cases and screening for high risk women.
乳腺癌是突尼斯女性癌症中的主要癌症。它占女性癌症的30%,每年约有1000例新病例。主要的干预控制措施是使用乳房X光检查进行大规模筛查,以降低乳腺癌死亡率。乳腺癌筛查在降低乳腺癌死亡率方面的效果与该癌症的发病率和生存率密切相关。国家家庭与人口办公室(ONFP)开展了一项使用乳房X光检查进行乳腺癌大规模筛查的试点经验。本研究的主要目的是计算通过ONFP的这一试点经验可能挽救的生命年数。对于方法,我们使用Dismod(疾病模型)软件来评估该省乳腺癌的患病率和病程,以及估计挽救的生命年数。对于50至69岁的女性,潜在的乳腺癌死亡率降低30%,对于40至49岁的女性,降低10%。根据突尼斯北部癌症登记数据库计算了1995 - 1998年期间阿丽亚娜地区按年龄划分的乳腺癌发病率。根据Dismod,在未进行筛查的情况下,40至49岁年龄组的平均病程为11.12年,50至69岁年龄组为9.57年。筛查将分别使40至49岁年龄组和50至69岁年龄组的这些平均病程增加2.22年和1.71年。1000名女性挽救的生命年数为2.97年。总之,在突尼斯使用乳房X光检查进行乳腺癌筛查实际上益处不大。乳房X光检查应保留用于疑似病例的诊断和高危女性的筛查。