细胞极性建立中广泛保守的信号通路。
Widely conserved signaling pathways in the establishment of cell polarity.
机构信息
Department of Microbiology, Center for Cell Signaling, University of Virginia School of Medicine, Charlottesville, Virginia 22908-5077, USA.
出版信息
Cold Spring Harb Perspect Biol. 2009 Aug;1(2):a001370. doi: 10.1101/cshperspect.a001370.
Abstract
How are the asymmetric distributions of proteins, lipids, and RNAs established and maintained in various cell types? Studies from diverse organisms show that Par proteins, GTPases, kinases, and phosphoinositides participate in conserved signaling pathways to establish and maintain cell polarity.
摘要
各种蛋白质、脂质和 RNA 在不同细胞类型中的不对称分布是如何建立和维持的？来自不同生物体的研究表明，Par 蛋白、GTPases、激酶和磷酸肌醇参与保守的信号通路，以建立和维持细胞极性。
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