Duke University Medical Center, Durham, NC 27710, USA.
J Vasc Surg. 2010 Apr;51(4 Suppl):9S-13S. doi: 10.1016/j.jvs.2009.10.129. Epub 2010 Jan 15.
This study evaluated gender-specific trends in the diagnosis and treatment of ruptured abdominal aortic aneurysms (rAAAs) in the United States Medicare population.
The Medicare beneficiary database (1995 through 2006) was examined for patients with rAAAs using International Classification of Diseaes, 9th Edition, Clinical Modification (ICD-9-CM) codes. Codes for endovascular aneurysm repair (EVAR) were only available for the year 2000 forward, and thus, analysis of EVAR was limited to 2000 through 2006. Proportions were analyzed by chi(2) and continuous variables by t-test. Factors associated with 30-day mortality and discharge home after surgery were analyzed by multivariate logistic regression. The effect of gender and repair type (open or EVAR) on death and the probability of discharge to home after repair were also evaluated.
The rate of hospitalizations per 100,000 Medicare fee-for-service beneficiaries for men decreased by 52% (from 40 to 19) and by 36% for women (from 11 to 7). The observed 30-day mortality rate was overall 7.7% higher for women vs men. The mortality rate for women was higher by 8.9% for open repair and higher by 7.1% for EVAR vs men. Female gender was associated with increased risk of death in multivariate analysis after controlling for age, year, and type of procedure. Women were 9.8% less likely to be discharged to home after rAAA repair, regardless of the type of repair.
In addition to the fact that we have failed to realize a change in the number of women diagnosed with or treated for rAAA, a significant gender difference remains in the outcomes after treatment for rAAA. This differential is present in both the 30-day mortality rate and in the potential to be discharged to home after repair.
本研究评估了美国医疗保险人群中破裂性腹主动脉瘤(rAAA)诊断和治疗的性别特异性趋势。
使用国际疾病分类第 9 版临床修订版(ICD-9-CM)代码,从 1995 年至 2006 年的医疗保险受益人群数据库中检查 rAAA 患者。血管内修复术(EVAR)的代码仅在 2000 年以后可用,因此,对 EVAR 的分析仅限于 2000 年至 2006 年。通过卡方检验分析比例,通过 t 检验分析连续变量。通过多变量逻辑回归分析与 30 天死亡率和手术后出院回家相关的因素。还评估了性别和修复类型(开放或 EVAR)对死亡和修复后出院回家的概率的影响。
男性每 10 万医疗保险付费受益人的住院率下降了 52%(从 40 例降至 19 例),女性下降了 36%(从 11 例降至 7 例)。观察到的 30 天死亡率女性总体比男性高 7.7%。开放修复女性死亡率比男性高 8.9%,EVAR 修复女性死亡率比男性高 7.1%。在控制年龄、年份和手术类型后,多变量分析显示女性性别与死亡风险增加相关。无论修复类型如何,女性 rAAA 修复后出院回家的可能性都降低了 9.8%。
除了我们未能实现女性诊断或治疗 rAAA 人数变化的事实之外,rAAA 治疗后结果仍存在显著的性别差异。这种差异既存在于 30 天死亡率,也存在于修复后出院回家的可能性。