Division of Nutrition, St. John's Medical College & Research Institute, St. John's National Academy of Health Sciences, Bangalore, India.
Indian J Med Res. 2009 Nov;130(5):600-8.
The prevalence of low birth weight (LBW) is higher in Asia than elsewhere, predominantly because of undernutrition of the mother prior to and during pregnancy. There are qualitative differences in dietary requirements during early and late pregnancy - micronutrients and proteins required in early pregnancy, and calories and other nutrients later. A paradigm shift from efforts to improve size at birth, to efforts to improve foetal growth and development might provide fresh insight into the problem. Micronutrient deficiencies during pregnancy have been shown to have serious implications on the developing foetus. Nearly half the pregnant women still suffer from varying degree of anaemia, with the highest prevalence in India, which also has the highest number of maternal deaths in the Asian region. Of specific concern is compliance with iron supplementation, cultural beliefs regarding diet in pregnancy, and the issue of nutrition supplementation and fortification. The coexistence of risk of LBW or intra uterine growth retardation (IUGR) associated with essential fatty acid docosahexaenoic acid (DHA) and vitamin B12 intake or status observed in the Indian sub-continent also requires further examination. There is a significant protective effect of higher maternal education (beyond high school). Optimal weight gain during pregnancy and a desirable foetal outcome may be a result of synergistic effects of improved food intake, food supplementation, improved micronutrient intake, education and the environment of the pregnant woman and her family.
低出生体重(LBW)的患病率在亚洲高于其他地区,主要是因为母亲在怀孕前和怀孕期间营养不良。孕早期和孕晚期的饮食需求存在质的差异——孕早期需要微量营养素和蛋白质,孕晚期需要卡路里和其他营养素。从努力改善出生时的体型转变为努力改善胎儿的生长和发育,可能会为解决这个问题提供新的思路。孕期微量营养素缺乏对发育中的胎儿有严重影响。近一半的孕妇仍患有不同程度的贫血,印度的贫血患病率最高,也是亚洲地区孕产妇死亡人数最多的国家。特别值得关注的是,铁补充的依从性、孕期饮食的文化观念以及营养补充和强化的问题。在印度次大陆观察到的与必需脂肪酸二十二碳六烯酸(DHA)和维生素 B12 摄入或状况相关的 LBW 或宫内生长迟缓(IUGR)风险共存也需要进一步研究。母亲的受教育程度较高(超过高中)有显著的保护作用。孕期体重增加和理想的胎儿结局可能是改善食物摄入、食物补充、改善微量营养素摄入、教育以及孕妇及其家庭环境的协同作用的结果。