Babol University of Medical Sciences, Babol, Iran.
Rheumatol Int. 2011 Jun;31(6):721-4. doi: 10.1007/s00296-009-1359-8. Epub 2010 Jan 21.
Brucellosis, an endemic disease in certain parts of the world is usually accompanied by osteoarticular involvement. The present study was performed to determine the types and frequency of rheumatologic manifestations in patients with brucellosis diagnosed in the north of Iran. Diagnosis of active brucellosis was based on the serological tests along with compatible clinical findings. Musculoskeletal involvement of brucellosis was confirmed by clinical and radiographic examinations; 51 (32 males, 19 females) patients with mean (SD) age of 35 (19) years old were studied. Rheumatological manifestations were observed in 94% of patients. The most frequent skeletal findings in order of frequency were peripheral arthritis, sacroiliitis; and spondylitis which occurred in 37; 31 and 8% of patients, respectively. Back pain, arthralgia, myalgia, and enthesopathy were also reported in 49, 34, 11.7% of patients, respectively. Based on the findings of this study, rheumatologic manifestations are common in brucellosis; therefore, in the endemic areas, brucellosis should be considered in the differential diagnosis of patients who present with any type of rheumatologic manifestations.
布鲁氏菌病是世界某些地区的地方性疾病,通常伴有骨关节炎受累。本研究旨在确定伊朗北部诊断为布鲁氏菌病患者的风湿表现类型和频率。活动性布鲁氏菌病的诊断基于血清学检查和相符的临床发现。布鲁氏菌病的肌肉骨骼受累通过临床和放射学检查得到确认;研究了 51 名(32 名男性,19 名女性)平均(SD)年龄为 35(19)岁的患者。94%的患者出现了风湿表现。最常见的骨骼表现按频率顺序依次为外周关节炎、骶髂关节炎和脊柱炎,分别发生在 37%、31%和 8%的患者中。背部疼痛、关节痛、肌痛和肌腱病也分别发生在 49%、34%和 11.7%的患者中。基于本研究的结果,风湿表现在布鲁氏菌病中很常见;因此,在流行地区,对于出现任何类型的风湿表现的患者,应考虑将布鲁氏菌病纳入鉴别诊断。