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[肾脏原发性双相性滑膜肉瘤]

[Primary biphasic synovial sarcoma of the kidney].

作者信息

Wezel F, Ströbel P, Michaely H, Michel M S, Häcker A

机构信息

Urologische Klinik, Universitätsmedizin Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim.

出版信息

Urologe A. 2010 Mar;49(3):411-4. doi: 10.1007/s00120-009-2209-8.

Abstract

Primary synovial sarcoma of the kidney is a rare neoplasm, which was first described by Argani et al. in 2000. We report a case of a 47-year-old man presenting with a renal mass of 11.7 x 9.3 x 8.1 cm size and a caval thrombus, which was classified as a biphasic differentiated spindle cell tumor. Fluorescence in situ hybridization (FISH) revealed a translocation t(X;18), specific for synovial sarcoma. In younger patients presenting with spindle cell-like renal tumors, a primary synovial sarcoma should be considered as a differential diagnosis.

摘要

原发性肾滑膜肉瘤是一种罕见的肿瘤,于2000年由阿尔加尼等人首次描述。我们报告一例47岁男性病例,其肾脏肿块大小为11.7×9.3×8.1厘米,并伴有腔静脉血栓形成,该肿瘤被分类为双相分化梭形细胞瘤。荧光原位杂交(FISH)显示存在滑膜肉瘤特有的t(X;18)易位。对于出现梭形细胞样肾肿瘤的年轻患者,应考虑原发性滑膜肉瘤作为鉴别诊断。

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