Nijs Jo, van Eupen Inge, Vandecauter Jo, Augustinus Els, Bleyen Geerte, Moorkens Greta, Meeus Mira
Vrije Universiteit Brussel, Building L-Mfys, Pleinlaan 2, BE-1050, Brussels, Belgium.
J Rehabil Res Dev. 2009;46(7):985-96. doi: 10.1682/jrrd.2009.01.0007.
Given the lack of evidence in support of pacing self-management for patients with chronic fatigue syndrome (CFS), we examined whether physical behavior and health status of patients with CFS would improve in response to a pacing self-management program. We performed an observational study of pacing self-management in seven CFS patients using a single-case study design. Stages A1 and A2 (7-day assessment periods) of the A1-B-A2 design corresponded to the baseline and posttreatment measurements of physical behavior (real-time activity monitoring) and health status (self-reported measures), respectively. Stage B (3 weeks of treatment) consisted of three individual treatment sessions of pacing self-management. When comparing pre- versus posttreatment data, we found that the patients' ability to perform daily activities and the severity of their symptom complexes were improved (p = 0.043). Concentration difficulties, mood swings, muscle weakness, and intolerance to bright light improved as well. A statistically significant decrease in the mean time spent doing light activity (<3 metabolic equivalents) was observed, but a change in the way physical activity was spread throughout the day was not. We found that 3 weeks of pacing self-management was accompanied by a modest improvement in symptom severity and daily functioning. The outcome of the present study calls for a randomized controlled clinical trial to examine the effectiveness of pacing self-management for people with CFS.
鉴于缺乏证据支持为慢性疲劳综合征(CFS)患者进行 pacing 自我管理,我们研究了 CFS 患者的身体行为和健康状况是否会因 pacing 自我管理计划而得到改善。我们采用单病例研究设计对 7 名 CFS 患者进行了 pacing 自我管理的观察性研究。A1-B-A2 设计的 A1 和 A2 阶段(7 天评估期)分别对应身体行为(实时活动监测)和健康状况(自我报告测量)的基线和治疗后测量。B 阶段(3 周治疗)包括三次 pacing 自我管理的个体治疗课程。比较治疗前和治疗后的数据时,我们发现患者进行日常活动的能力和症状复合体的严重程度有所改善(p = 0.043)。注意力不集中、情绪波动、肌肉无力和对强光不耐受的情况也有所改善。观察到进行轻度活动(<3 代谢当量)的平均时间有统计学意义的减少,但全天身体活动分布方式没有变化。我们发现 3 周的 pacing 自我管理伴随着症状严重程度和日常功能的适度改善。本研究的结果呼吁进行一项随机对照临床试验,以检验 pacing 自我管理对 CFS 患者的有效性。