Division of Biomedical Engineering, Indian Institute of Technology Madras, Chennai 600036, India.
IEEE Trans Biomed Eng. 2010 May;57(5):1167-75. doi: 10.1109/TBME.2009.2037606. Epub 2010 Feb 5.
The normalized backscattered intensity (NBI) profiles at various locations of human thorax by multiprobe laser reflectometer are obtained. These data after digitization, interpolation, and filtering are color-coded and displayed as images on the outline of the human thorax. For optical characterization of tissues in terms of their parameters, scattering and absorption coefficients and the anisotropy parameter (g) are obtained by matching the measured NBI profile with that as obtained by Monte Carlo simulation procedure. Corresponding to the variation of the NBI over the various regions, the optical parameters show their respective changes. The maximum absorption and minimum scattering coefficients are observed at the areola, clavicle, sternum, scapula, and vertebral column. The minimum absorption and maximum scattering coefficients are observed at the pectoralis major of chest and rectus abdominis of abdomen regions, as compared to the other regions, attributed to their tissue compositional variations. To visualize the various tissues in lower regions of the thorax, the color-coded scheme of the NBI variation, as measured by the third fiber, is further expanded. By this procedure, the outlines of the heart and lungs, as detected through intercostals regions, are observed, which is in good agreement with that as determined by the chest radiograph of the same subject taken in PA position. Similarly the lower sections of the liver and stomach, due to their distinct optical parameters, are also observed.
利用多探针激光反射计获得了人体胸部不同位置的归一化反向散射强度(NBI)分布。这些经过数字化、插值和滤波处理后的数据被进行颜色编码,并以人体胸部轮廓的图像形式显示。为了从参数、散射和吸收系数以及各向异性参数(g)的角度对组织进行光学特性描述,通过将测量得到的 NBI 分布与蒙特卡罗模拟程序得到的分布进行匹配,得到了这些光学参数。与 NBI 在各个区域的变化相对应,光学参数也显示出相应的变化。在乳晕、锁骨、胸骨、肩胛骨和脊柱等区域,吸收系数最大,散射系数最小。在胸部的胸大肌和腹部的腹直肌等区域,吸收系数最小,散射系数最大,这归因于这些区域的组织成分变化。为了可视化胸部下部的各种组织,进一步扩展了由第三根光纤测量的 NBI 变化的颜色编码方案。通过这种方法,可以观察到通过肋间隙区域检测到的心脏和肺部的轮廓,这与在 PA 位置拍摄的同一受试者的胸部 X 光片确定的结果非常吻合。同样,由于其独特的光学参数,也可以观察到肝和胃的下部区域。