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在准分子激光辅助非闭吻合旁路保护下夹闭巨大动脉瘤。

Giant aneurysm clipping under protection of an excimer laser-assisted non-occlusive anastomosis bypass.

机构信息

Rudolf Magnus Institute of Neuroscience, Department of Neurosurgery, University Medical Center Utrecht, Utrecht, The Netherlands.

出版信息

Neurosurgery. 2010 Mar;66(3):439-47; discussion 447. doi: 10.1227/01.NEU.0000364998.95710.73.

Abstract

OBJECTIVE

To define the safety and clinical value of giant aneurysm clipping under protection of an excimer laser-assisted non-occlusive anastomosis (ELANA) bypass.

METHODS

We report 32 patients with an uncoilable intracerebral giant aneurysm, operated on with the aid of an ELANA protective bypass between January 1, 1994, and January 1, 2008. We retrospectively collected data from patient records. Follow-up data were updated by telephone interview. We defined a favorable outcome as a successfully treated aneurysm and a better or equal postoperative modified Rankin scale (mRS) score compared with the preoperative mRS.

RESULTS

In total 33 bypasses were constructed, of which 31 (94%) were patent during the rest of the procedure. The first failed bypass was salvaged during a second procedure. Of the second failed bypass, the ELANA anastomosis could be reused during second bypass surgery. All 32 aneurysms could be treated. The bypasses served as protection during temporary parent vessel occlusion (n = 24, 75%), control during aneurysm rupture (n = 3, 9%), and in all patients as an indicator for recipient artery narrowing during clip placement. Four bypasses (12%) eventually had to partially (n = 3) or fully (n = 1) replace recipient artery flow at the end of surgery. Postoperatively, 3 patients (9%) had a hemorrhagic complication and 2 patients (6%) had an ischemic complication. At long-term follow-up (mean, 6.1 +/- 3.4 y), 28 patients (88%) had a favorable functional outcome.

CONCLUSION

The ELANA protective bypass is a safe and useful instrument for the treatment of these difficult aneurysms.

摘要

目的

确定在准分子激光辅助非闭塞吻合术(ELANA)旁路保护下夹闭巨大动脉瘤的安全性和临床价值。

方法

我们报告了 1994 年 1 月 1 日至 2008 年 1 月 1 日期间,在 ELANA 保护旁路辅助下手术的 32 例不可解颅内巨大动脉瘤患者。我们回顾性地从患者病历中收集数据。通过电话访谈更新随访数据。我们将良好的结果定义为成功治疗的动脉瘤和术后改良 Rankin 量表(mRS)评分较术前更好或相等。

结果

共构建了 33 个旁路,其中 31 个(94%)在手术的其余部分是通畅的。第一个失败的旁路在第二次手术中被抢救。第二个失败的旁路中,ELANA 吻合术可在第二次旁路手术中重新使用。所有 32 个动脉瘤均能得到治疗。旁路在临时血管闭塞期间(n=24,75%)、动脉瘤破裂时(n=3,9%)以及在所有患者夹闭期间作为受体动脉狭窄的指示物(n=32)提供保护。最终,有 4 个旁路(12%)在手术结束时需要部分(n=3)或完全(n=1)替代受体动脉血流。术后,3 名患者(9%)发生出血性并发症,2 名患者(6%)发生缺血性并发症。长期随访(平均 6.1+/-3.4 年),28 名患者(88%)的功能预后良好。

结论

ELANA 保护旁路是治疗这些困难动脉瘤的一种安全且有用的工具。

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