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土耳其阿菲永卡拉希萨尔地区土耳其妇女和儿童中风疹的血清流行率。

Seroprevalence of rubella among Turkish women and children in Afyonkarahisar, Turkey.

作者信息

Demirdal Tuna, Demirtürk Neşe, Toprak Dilek, Aktepe Orhan C, Aşci Zerrin

机构信息

Department of Infectious Diseases and Clinical Microbiology, Kocatepe University Faculty of Medicine, Afyonkarahisar, Turkey.

出版信息

Turk J Pediatr. 2009 Nov-Dec;51(6):534-8.

Abstract

The objective of this study was to determine the seroprevalence of rubella virus infection among women and female children/youth (0- 17-years-old) in Afyonkarahisar, Turkey. This study was conducted between November 2005 and February 2006. One thousand four hundred nine serum specimens were studied by the enzyme-linked immunosorbent assay (ELISA) method. Age, educational level, economic and marital status, smoking habit, application or not of measles-mumps-rubella (MMR) vaccination, and previous skin rash of the patients included in the study were questioned and noted. Positive rubella-specific IgG antibodies prevalence was found as 18.5% in girls between 0-1 years of age, 28.6% in girls between 2-6 years of age, 36.8% in girls between 7-17 years of age, and 80.0%, 80.9%, 78.5%, 73.7% and 78.1% in women between 18-20, 21-30, 31-40, 41-50, and 50+ years of age, respectively. There were no statistically significant correlations between immunity to rubella and other sociodemographic characteristics. In conclusion, nearly 20% of women of reproductive age are sensitive to rubella and should be vaccinated. The clear effects of adding MMR to the routine vaccination schedule will be observed in the following years in Turkey.

摘要

本研究的目的是确定土耳其阿菲永卡拉希萨尔地区0至17岁女性和女童/青年风疹病毒感染的血清流行率。本研究于2005年11月至2006年2月进行。采用酶联免疫吸附测定(ELISA)法对1409份血清标本进行了研究。对纳入研究的患者的年龄、教育程度、经济和婚姻状况、吸烟习惯、是否接种麻疹-腮腺炎-风疹(MMR)疫苗以及既往皮疹情况进行了询问并记录。结果发现,0至1岁女童风疹特异性IgG抗体阳性率为18.5%,2至6岁女童为28.6%,7至17岁女童为36.8%,18至20岁、21至30岁、31至40岁、41至50岁以及50岁以上女性的阳性率分别为80.0%、80.9%、78.5%、73.7%和78.1%。风疹免疫力与其他社会人口学特征之间无统计学显著相关性。总之,近20%的育龄妇女对风疹敏感,应接种疫苗。在土耳其,未来几年将观察到在常规疫苗接种计划中添加MMR疫苗的明显效果。

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