Department of Perioperative Medicine and Intensive Care, San Gerardo Hospital, University of Milano-Bicocca, Monza, Italy.
Respir Care. 2010 Mar;55(3):294-302.
Recent data suggest that during mechanical ventilation the lateral-horizontal patient position (in which the endotracheal tube is horizontal) decreases the risk of ventilator-associated pneumonia, compared to the recommended semi-recumbent position (in which the endotracheal tube slopes downward into the trachea). We tested the feasibility of the lateral-horizontal patient position, measured the incidence of aspiration of gastric contents, and watched for any adverse effects related to the lateral-horizontal position.
Ten adult intensive care unit patients were ventilated for 64 hours in the standard semi-recumbent position, and ten for 12-24 hours in the lateral-horizontal position. Tracheal secretions were collected every 8 hours and every 4 hours, respectively, and tested for pepsin, which is a marker of gastric contents. We also recorded clinical, physiologic, and outcome variables.
The patients remained stable during ventilation in the lateral-horizontal position, and no adverse events occurred. Pepsin was detected in the trachea of 7 semi-recumbent patients and in five of the lateral-horizontal patients (P = .32). The number of ventilator-free days was 8 days (range 0-21 days) in the semi-recumbent patients, versus 24 days (range 12-25 days) in the lateral-horizontal patients (P = .04).
Implementing the lateral-horizontal position for 12-24 hours in adult intubated intensive care unit patients is feasible, and our patients had no adverse events. The incidence of aspiration of gastric contents in the lateral-horizontal position seems to be similar to that in the semi-recumbent position.
最近的数据表明,与推荐的半卧位(气管插管向气管下倾)相比,机械通气时,使患者侧卧水平位(气管插管呈水平位)可降低呼吸机相关性肺炎的风险。我们测试了侧卧水平位的可行性,测量了胃内容物吸入的发生率,并观察了与侧卧水平位相关的任何不良反应。
10 名成人重症监护病房患者在标准半卧位通气 64 小时,10 名患者在侧卧水平位通气 12-24 小时。分别每 8 小时和每 4 小时收集气管分泌物,并检测胃蛋白酶,这是胃内容物的标志物。我们还记录了临床、生理和结局变量。
患者在侧卧水平位通气时保持稳定,未发生不良事件。7 名半卧位患者和 5 名侧卧水平位患者的气管中均检测到胃蛋白酶(P=.32)。半卧位患者的无呼吸机天数为 8 天(范围 0-21 天),而侧卧水平位患者为 24 天(范围 12-25 天)(P=.04)。
在成人插管重症监护病房患者中实施侧卧水平位 12-24 小时是可行的,我们的患者没有发生不良事件。侧卧水平位时胃内容物吸入的发生率似乎与半卧位相似。