[番石榴果实中的三萜类成分]

[Triterpenoid constituents in fruits of Psidum guajava].

作者信息

Shu Jicheng, Chou Guixin, Wang Zhengtao

机构信息

Key Laboratory of Standardization of Chinese Medicines, Shanghai R&D Center for standardization of Chinese Medicines, Ministry of Education, Institute of Chinese Materia Medica of Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2009 Dec;34(23):3047-50.

PMID:20222421

Abstract

The chemical constituents from the fruit of Psidium guajava were investigated. Nine triterpenoids, ursolic acid (1), 1beta, 3beta-dihydroxyurs-12-en-28-oic acid (2), 2alpha,3beta-dihydroxyurs-12-en-28-oic acid (3), 3beta,19alpha-dihydroxyurs-12en-28-oic acid (4), 19a-hydroxylurs-12-en-28-oic acid-3-O-alpha-L-arabinopyranoside (5), 3beta, 23-dihydroxy urs-12-en-28-oic acid (6), 3beta, 19alpha, 23beta-tri-hydroxylurs-12-en-28-oic acid (7), 2alpha, 3beta,19alpha, 23beta-tetrahydroxyurs-12-en-28-oic acid (8), 3alpha,19alpha,23,24-tetrahydroxyurs -12-en-28-oic acid (9) were isolated by means of chromatography, and their structures were elucidated on the basis of MS, H NMR, 13C-NMR spectra. Compounds 2, 5-9 were isolated from this plant for the first time.

摘要

对番石榴果实的化学成分进行了研究。通过色谱法分离得到9种三萜类化合物，熊果酸（1）、1β，3β - 二羟基乌苏 - 12 - 烯 - 28 - 酸（2）、2α，3β - 二羟基乌苏 - 12 - 烯 - 28 - 酸（3）、3β，19α - 二羟基乌苏 - 12 - 烯 - 28 - 酸（4）、19α - 羟基乌苏 - 12 - 烯 - 28 - 酸 - 3 - O - α - L - 阿拉伯吡喃糖苷（5）、3β，23 - 二羟基乌苏 - 12 - 烯 - 28 - 酸（6）、3β，19α，23β - 三羟基乌苏 - 12 - 烯 - 28 - 酸（7）、2α，3β，19α，23β - 四羟基乌苏 - 12 - 烯 - 28 - 酸（8）、3α，19α，23，24 - 四羟基乌苏 - 12 - 烯 - 28 - 酸（9），并根据质谱、氢核磁共振、碳 - 13核磁共振光谱对其结构进行了阐明。化合物2、5 - 9首次从该植物中分离得到。