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患者相关结局 7 年后全髋关节置换术治疗 OA-一项前瞻性研究。

Patient relevant outcome 7 years after total hip replacement for OA - a prospective study.

机构信息

Department Orthopedics, Lund University, Lund, Sweden.

出版信息

BMC Musculoskelet Disord. 2010 Mar 11;11:47. doi: 10.1186/1471-2474-11-47.

Abstract

BACKGROUND

To investigate prospectively the patient-relevant outcome 7 years after total hip replacement (THR) for osteoarthritis (OA).

METHODS

219 consecutive patients (120 women) with primary OA, mean age 71 (range 50-92) were assigned for THR. They were examined preoperatively, at 3, 6, 12 months, and at 4, 5 and 7 years postoperatively with the self-administered questionnaires SF-36 and WOMAC. Supplementary questions regarding postoperative complications, general co-morbidity, social circumstances and patient satisfaction were asked at the three last follow-ups. A reference group, 117 subjects (67 women), mean age 72 (range 52-92) without hip complaints were recruited from the community and investigated at the same times.

RESULTS

151/170 (89%) of the patients and 65/74 (88%) of the reference group participated at the 7 year follow-up. The best postoperative result was reported one year postoperatively. At the 7 year follow up there was a significant difference between the patients and controls in SF-36 physical function (PF) and role physical (RP) but not of WOMAC function. There was no difference in frequency of co-morbid conditions between those operated and the reference group, but those operated were in greater need of walking aid (46% vs. 8% p < 0.0001) and reported more regional and widespread pain (68% vs. 53% p < 0.05).

CONCLUSION

This study shows that in an unselected cohort the patients experience a similar health-related quality of life as a reference group of a similar age and sex structure 7 years after THR except for general physical function where the patients score worse.

摘要

背景

前瞻性研究全髋关节置换术(THR)治疗骨关节炎(OA)7 年后的患者相关结局。

方法

219 例原发性 OA 连续患者(120 例女性),平均年龄 71 岁(范围 50-92 岁),接受 THR 治疗。他们在术前、术后 3、6、12 个月以及术后 4、5 和 7 年接受自我管理问卷 SF-36 和 WOMAC 评估。在最后 3 次随访时,还询问了与术后并发症、一般合并症、社会情况和患者满意度相关的补充问题。从社区招募了 117 名(67 名女性)无髋关节抱怨的对照组受试者,平均年龄 72 岁(范围 52-92 岁),并在相同时间进行了调查。

结果

170 例患者中有 151 例(89%)和 74 例对照组中有 65 例(88%)在 7 年随访时参与了研究。术后最佳结果报告于术后 1 年。在 7 年随访时,患者组与对照组在 SF-36 身体功能(PF)和角色身体(RP)方面存在显著差异,但 WOMAC 功能方面无差异。手术组和对照组的合并症频率没有差异,但手术组更需要助行器(46% vs. 8%,p<0.0001),并报告更多的区域和广泛疼痛(68% vs. 53%,p<0.05)。

结论

本研究表明,在未选择的队列中,除了一般身体功能外,患者在 THR 后 7 年的健康相关生活质量与相似年龄和性别结构的对照组相似。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba8/2847954/81e1253896c4/1471-2474-11-47-1.jpg

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