Błachnio Maria, Zielonka Tadeusz M, Rzewuska Ewa, Mioduszewska Olga, Maryniak Renata, Błachnio Antoni
Mazowieckie Centrum Leczenia Chorób Płuc i Gruźlicy w Otwocku.
Wiad Lek. 2009;62(3):168-72.
Spleen is a rare extra-pulmonary tuberculosis manifestation. The spleen tuberculosis is caused by the blood derivative dissemination of mycobacteria. The symptoms can suggest a hematological disease, but it is difficult to make a diagnosis, especially when there are no pulmonary changes. The case of a 27-year-old woman with unclear etiology bone marrow hypoplasia was presented. The patient experienced: fever, body weight loss, pancytopenia and spleen enlargement with numerous focal echographic changes. The splenectomy revealed in a histopathologic examination productiva caseosa tuberculosis. The bone marrow trepanobiopsy revealed as well tuberculosis changes. The antimycobacteria treatment caused an improvement of the clinical state and the regression of symptoms.
脾脏是一种罕见的肺外结核表现形式。脾结核是由分枝杆菌经血行播散引起的。其症状可能提示血液系统疾病,但诊断困难,尤其是在没有肺部病变的情况下。本文介绍了一名27岁病因不明的骨髓发育不全女性病例。该患者有发热、体重减轻、全血细胞减少以及脾脏肿大并伴有多处局灶性超声图像改变。脾切除术后的组织病理学检查显示为干酪样结核。骨髓环钻活检也显示有结核改变。抗分枝杆菌治疗使临床状况得到改善,症状消退。