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[脾与髓质结核]

[Spleen and medullary tuberculosis].

作者信息

Błachnio Maria, Zielonka Tadeusz M, Rzewuska Ewa, Mioduszewska Olga, Maryniak Renata, Błachnio Antoni

机构信息

Mazowieckie Centrum Leczenia Chorób Płuc i Gruźlicy w Otwocku.

出版信息

Wiad Lek. 2009;62(3):168-72.

Abstract

Spleen is a rare extra-pulmonary tuberculosis manifestation. The spleen tuberculosis is caused by the blood derivative dissemination of mycobacteria. The symptoms can suggest a hematological disease, but it is difficult to make a diagnosis, especially when there are no pulmonary changes. The case of a 27-year-old woman with unclear etiology bone marrow hypoplasia was presented. The patient experienced: fever, body weight loss, pancytopenia and spleen enlargement with numerous focal echographic changes. The splenectomy revealed in a histopathologic examination productiva caseosa tuberculosis. The bone marrow trepanobiopsy revealed as well tuberculosis changes. The antimycobacteria treatment caused an improvement of the clinical state and the regression of symptoms.

摘要

脾脏是一种罕见的肺外结核表现形式。脾结核是由分枝杆菌经血行播散引起的。其症状可能提示血液系统疾病,但诊断困难,尤其是在没有肺部病变的情况下。本文介绍了一名27岁病因不明的骨髓发育不全女性病例。该患者有发热、体重减轻、全血细胞减少以及脾脏肿大并伴有多处局灶性超声图像改变。脾切除术后的组织病理学检查显示为干酪样结核。骨髓环钻活检也显示有结核改变。抗分枝杆菌治疗使临床状况得到改善,症状消退。

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