Horré Regine, Lackner Michaela, Buzina Walter, Tintelnot Kathrin
Institut für Medizinische Mikrobiologie, Immunologie und Parasitologie des Universitätsklinikums Bonn.
Anasthesiol Intensivmed Notfallmed Schmerzther. 2010 Mar;45(3):152-8. doi: 10.1055/s-0030-1249395. Epub 2010 Mar 15.
Brain infections caused by fungi of the Pseudallescheria / Scedosporium-complex weeks or months after a near drowning event should be considered, since mortality rate is high and specific diagnostic methods are necessary for fungal detection. Voriconazole is the only authorised antimycotic drug available for the treatment of these infections in Germany, but other antimycotics may also be indicated for alternate or combined treatment strategies. Consultation of a specific reference laboratory is recommended in comparable relevant cases.
在近乎溺水事件数周或数月后,由拟阿利什霉属/帚霉属复合真菌引起的脑部感染应予以考虑,因为死亡率很高,且需要特定的诊断方法来检测真菌。伏立康唑是德国唯一获批用于治疗这些感染的抗真菌药物,但其他抗真菌药物也可能适用于替代或联合治疗策略。在类似的相关病例中,建议咨询特定的参考实验室。