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182 例 ROKITANSKY 综合征患者经颅外阴道成形术联合盆腔腹膜移植的长期疗效。

Long-term outcomes of transvestibular vaginoplasty with pelvic peritoneum in 182 patients with Rokitansky's syndrome.

机构信息

Department of Gynecology, Women's Hospital, School of Medicine, Zhejiang University, Zhejiang, People's Republic of China.

出版信息

Fertil Steril. 2010 Nov;94(6):2281-5. doi: 10.1016/j.fertnstert.2010.02.010. Epub 2010 Mar 19.

Abstract

OBJECTIVE

To evaluate the technical feasibility and anatomical and functional outcomes of one-stage transvestibular vaginoplasty with pelvic peritoneum for the patients with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome.

DESIGN

A retrospective review of prospectively collected data.

SETTING

A university hospital.

PATIENT(S): A total of 182 women with MRKH syndrome.

INTERVENTION(S): Undergoing transvestibular vaginoplasty with pelvic peritoneum.

MAIN OUTCOME MEASURE(S): The perioperative results, complications, and anatomical and functional outcomes of transvestibular vaginoplasty with pelvic peritoneum.

RESULT(S): The mean operative time was 72.2 minutes (range 55-150 minutes). Average blood loss was 78.5 mL (range 40-170 mL). The only perioperative complication was one case of rectal-vaginal fistula. Thirty-four patients had vault granulation at the neovagina, which healed after trimming and the mean length of the neovagina was 9 cm (range 7-12 cm) without any shrinkage at the follow-up of 3 months after operation. The neovaginal introitus admitted two fingers in width in all patients. Good functional outcomes were found in the patients at follow-up 15 years after surgery with 80% of the cumulative proportion of sexual satisfactory activity.

CONCLUSION(S): Transvestibular vaginoplasty with pelvic peritoneum is an effective and feasible approach for women with MRKH syndrome. The procedure has satisfactory long-term anatomical and functional results.

摘要

目的

评估经前庭阴道成形术联合盆腔腹膜一期成形术治疗 Mayer-Rokitansky-Kuster-Hauser(MRKH)综合征患者的技术可行性、解剖学和功能结果。

设计

前瞻性收集数据的回顾性研究。

地点

一所大学医院。

患者

共 182 例 MRKH 综合征患者。

干预

行经前庭阴道成形术联合盆腔腹膜一期成形术。

主要观察指标

经前庭阴道成形术联合盆腔腹膜一期成形术的围手术期结果、并发症,以及解剖学和功能结果。

结果

平均手术时间为 72.2 分钟(55-150 分钟)。平均失血量为 78.5 毫升(40-170 毫升)。唯一的围手术期并发症是 1 例直肠阴道瘘。34 例患者的阴道顶有肉芽组织,经修剪后愈合,术后 3 个月随访时阴道平均长度为 9 厘米(7-12 厘米),无收缩。所有患者的阴道入口可容纳 2 指宽度。术后 15 年随访时,患者的功能结果良好,有 80%的累积性性行为满意活动比例。

结论

经前庭阴道成形术联合盆腔腹膜一期成形术是治疗 MRKH 综合征患者的一种有效且可行的方法。该手术具有满意的长期解剖学和功能结果。

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