Department of Gynecology, Women's Hospital, School of Medicine, Zhejiang University, Zhejiang, People's Republic of China.
Fertil Steril. 2010 Nov;94(6):2281-5. doi: 10.1016/j.fertnstert.2010.02.010. Epub 2010 Mar 19.
To evaluate the technical feasibility and anatomical and functional outcomes of one-stage transvestibular vaginoplasty with pelvic peritoneum for the patients with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome.
A retrospective review of prospectively collected data.
A university hospital.
PATIENT(S): A total of 182 women with MRKH syndrome.
INTERVENTION(S): Undergoing transvestibular vaginoplasty with pelvic peritoneum.
MAIN OUTCOME MEASURE(S): The perioperative results, complications, and anatomical and functional outcomes of transvestibular vaginoplasty with pelvic peritoneum.
RESULT(S): The mean operative time was 72.2 minutes (range 55-150 minutes). Average blood loss was 78.5 mL (range 40-170 mL). The only perioperative complication was one case of rectal-vaginal fistula. Thirty-four patients had vault granulation at the neovagina, which healed after trimming and the mean length of the neovagina was 9 cm (range 7-12 cm) without any shrinkage at the follow-up of 3 months after operation. The neovaginal introitus admitted two fingers in width in all patients. Good functional outcomes were found in the patients at follow-up 15 years after surgery with 80% of the cumulative proportion of sexual satisfactory activity.
CONCLUSION(S): Transvestibular vaginoplasty with pelvic peritoneum is an effective and feasible approach for women with MRKH syndrome. The procedure has satisfactory long-term anatomical and functional results.
评估经前庭阴道成形术联合盆腔腹膜一期成形术治疗 Mayer-Rokitansky-Kuster-Hauser(MRKH)综合征患者的技术可行性、解剖学和功能结果。
前瞻性收集数据的回顾性研究。
一所大学医院。
共 182 例 MRKH 综合征患者。
行经前庭阴道成形术联合盆腔腹膜一期成形术。
经前庭阴道成形术联合盆腔腹膜一期成形术的围手术期结果、并发症,以及解剖学和功能结果。
平均手术时间为 72.2 分钟(55-150 分钟)。平均失血量为 78.5 毫升(40-170 毫升)。唯一的围手术期并发症是 1 例直肠阴道瘘。34 例患者的阴道顶有肉芽组织,经修剪后愈合,术后 3 个月随访时阴道平均长度为 9 厘米(7-12 厘米),无收缩。所有患者的阴道入口可容纳 2 指宽度。术后 15 年随访时,患者的功能结果良好,有 80%的累积性性行为满意活动比例。
经前庭阴道成形术联合盆腔腹膜一期成形术是治疗 MRKH 综合征患者的一种有效且可行的方法。该手术具有满意的长期解剖学和功能结果。