Epelman Monica, Kreiger Portia A, Servaes Sabah, Victoria Teresa, Hellinger Jeffrey C
Department of Radiology, the Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA 19104, USA.
Semin Ultrasound CT MR. 2010 Apr;31(2):141-57. doi: 10.1053/j.sult.2010.01.002.
Congenital lung lesions refer to a spectrum of pulmonary developmental anomalies including, but not limited to, bronchial atresia, congenital pulmonary airway malformation (formerly known as congenital cystic adenomatoid malformation) and bronchopulmonary sequestration. These anomalies comprise about 90% of the anomalies seen in clinical practice. The advent of prenatal sonography and, more recently, fetal magnetic resonance imaging has changed our understanding and practice in the evaluation of congenital lung lesions. Postnatal imaging using low-dose computed tomography angiography (CTA) is extremely useful as it may provide information essential for differential diagnosis by allowing multiplanar reconstructions of the airway, lung parenchyma, and vasculature. The use of iodine in CTA permits the application of low-dose radiation protocols in these young patients. The purpose of this article is to emphasize the technical factors that may optimize low-dose CTA evaluation of these lesions. We also provide a description of prenatal imaging findings and helpful diagnostic clues that may be useful for the characterization of the most commonly encountered prenatally diagnosed pulmonary developmental anomalies.
先天性肺部病变是指一系列肺部发育异常,包括但不限于支气管闭锁、先天性肺气道畸形(以前称为先天性囊性腺瘤样畸形)和肺隔离症。这些异常约占临床实践中所见异常的90%。产前超声检查的出现,以及最近胎儿磁共振成像的出现,改变了我们对先天性肺部病变评估的理解和实践。使用低剂量计算机断层血管造影(CTA)进行产后成像非常有用,因为它可以通过对气道、肺实质和血管系统进行多平面重建,提供对鉴别诊断至关重要的信息。CTA中碘的使用允许在这些年轻患者中应用低剂量辐射方案。本文的目的是强调可能优化这些病变低剂量CTA评估的技术因素。我们还描述了产前影像学表现以及有助于诊断的线索,这些可能有助于对产前诊断最常见的肺部发育异常进行特征性描述。