Shekelle R B, Vernon S W, Ostfeld A M
University of Texas School of Public Health, Houston.
Psychosom Med. 1991 Mar-Apr;53(2):176-84. doi: 10.1097/00006842-199103000-00007.
Three MMPI variables--HsK + Hy, neuroticism, and somatic complaints--were positively associated with incidence of uncomplicated angina pectoris and not significantly associated with incidence of myocardial infarction and coronary death in a 10-year cohort study of 2003 employed middle-aged men. All three were negatively associated with risk of coronary death after the diagnosis of uncomplicated angina had been established. These results support the hypothesis that tendencies to report somatic complaints or to experience negative, distressing emotions chronically are not related to incidence of coronary heart disease but are associated with incidence of a relative benign, nonatherosclerotic condition that is similar clinically to angina pectoris. Also, HsK + Hy and somatic complaints were positively associated with risk of coronary death in men who had survived an initial myocardial infarction. This result does not indicate an association with coronary hearth disease itself because all of these men already had coronary heart disease. This result may indicate that the tendency to report somatic complaints is related to increased susceptibility to acute emotional stressors that can trigger arrhythmias in an ischemic myocardium.
在一项针对2003名在职中年男性的10年队列研究中,明尼苏达多相人格调查表(MMPI)的三个变量——HsK + Hy、神经质和躯体主诉——与单纯性心绞痛的发病率呈正相关,而与心肌梗死和冠状动脉死亡的发病率无显著关联。在确诊单纯性心绞痛后,这三个变量均与冠状动脉死亡风险呈负相关。这些结果支持了这样一种假设,即报告躯体主诉或长期经历消极、痛苦情绪的倾向与冠心病的发病率无关,但与一种相对良性的、非动脉粥样硬化性疾病的发病率有关,这种疾病在临床上与心绞痛相似。此外,HsK + Hy和躯体主诉与首次心肌梗死后存活的男性的冠状动脉死亡风险呈正相关。这一结果并不表明与冠心病本身存在关联,因为所有这些男性都已经患有冠心病。这一结果可能表明,报告躯体主诉的倾向与对急性情绪应激源的易感性增加有关,这些应激源可在缺血心肌中引发心律失常。