嘌呤能信号的发生和产后发育。
The birth and postnatal development of purinergic signalling.
机构信息
Autonomic Neuroscience Centre, Royal Free and University College Medical School, London, UK.
出版信息
Acta Physiol (Oxf). 2010 Jun;199(2):93-147. doi: 10.1111/j.1748-1716.2010.02114.x. Epub 2010 Mar 24.
Abstract
The purinergic signalling system is one of the most ancient and arguably the most widespread intercellular signalling system in living tissues. In this review we present a detailed account of the early developments and current status of purinergic signalling. We summarize the current knowledge on purinoceptors, their distribution and role in signal transduction in various tissues in physiological and pathophysiological conditions.
摘要
嘌呤能信号系统是最古老的细胞间信号系统之一，可以说是生物组织中分布最广泛的信号系统之一。在这篇综述中，我们详细介绍了嘌呤能信号的早期发展和现状。我们总结了目前关于嘌呤能受体及其在生理和病理生理条件下各种组织中信号转导中的分布和作用的知识。
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