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[心脏病患者的非心脏手术]

[Non-cardiac surgery in patients with cardiac disease].

作者信息

Sellevold Olav F Münter, Stenseth Roar

机构信息

Institutt for sirkulasjon og bildedannelse, Norges teknisk-naturvitenskapelige universitet og St. Olavs hospital, Prinsesse Kristinas gate 3, 7030 Trondheim, Norway.

出版信息

Tidsskr Nor Laegeforen. 2010 Mar 25;130(6):623-7. doi: 10.4045/tidsskr.08.0309.

Abstract

BACKGROUND

Patients with cardiac disease have a higher incidence of cardiovascular events after non-cardiac surgery than those without such disease. This paper provides an overview of perioperative examinations and treatment.

MATERIAL AND METHODS

Own experience and systematic literature search through work with European guidelines constitute the basis for recommendations given in this article.

RESULTS

Beta-blockers should not be discontinued before surgery. High-risk patients may benefit from beta-blockers administered before major non-cardiac surgery. Slow dose titration is recommended. Echocardiography should be performed before preoperative beta-blockade to exclude latent heart failure. Statins should be considered before elective surgery and coronary intervention (stenting or surgery) before high-risk surgery. Otherwise, interventions should be evaluated irrespective of planned non-cardiac surgery. Patients with unstable coronary syndrome should only undergo non-cardiac surgery on vital indications. Neuraxial techniques are optimal for postoperative pain relief and thus for postoperative mobilization. Thromboprophylaxis is important, but increases the risk of epidural haematoma and requires systematic follow-up with respect to diagnostics and treatment.

INTERPRETATION

Little evidence supports the use of different anaesthetic methods in cardiac patients that undergo non-cardiac surgery than in other patients. Stable circulation, sufficient oxygenation, good pain relief, thromboprophylaxis, enteral nutrition and early mobilization are important factors for improving the perioperative course. Close cooperation between anaesthesiologist, surgeon and cardiologist improves logistics and treatment.

摘要

背景

患有心脏病的患者在非心脏手术后发生心血管事件的发生率高于无心脏病的患者。本文概述了围手术期的检查和治疗。

材料与方法

本文给出的建议基于自身经验以及通过参照欧洲指南开展的系统文献检索。

结果

β受体阻滞剂在手术前不应停用。高危患者可能从大型非心脏手术前给予的β受体阻滞剂中获益。建议缓慢滴定剂量。在术前使用β受体阻滞剂前应进行超声心动图检查以排除潜在心力衰竭。在择期手术前应考虑使用他汀类药物,对于高危手术,应在术前进行冠状动脉介入治疗(支架置入或手术)。否则,无论计划进行何种非心脏手术,都应对干预措施进行评估。患有不稳定型冠状动脉综合征的患者仅在有生命指征时才应接受非心脏手术。神经轴技术对于术后疼痛缓解以及术后活动的促进最为理想。血栓预防很重要,但会增加硬膜外血肿的风险,需要在诊断和治疗方面进行系统随访。

解读

几乎没有证据支持在接受非心脏手术的心脏病患者中使用与其他患者不同的麻醉方法。稳定的循环、充足的氧合、良好的疼痛缓解、血栓预防、肠内营养和早期活动是改善围手术期过程的重要因素。麻醉医生、外科医生和心脏病专家之间的密切合作可改善后勤保障和治疗效果。

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