Almas Aysha, Parkash Om, Hameed Aamir, Islam Muhammad
Department of Medicine, The Aga Khan University, Karachi.
J Coll Physicians Surg Pak. 2010 Feb;20(2):74-8.
To determine the sensitivity and specificity of initial clinical assessment about the diagnosis of acute coronary syndrome (ACS) in patients presenting with acute chest pain by a cardiology resident in the emergency room and assess the 30-day outcome of patients with ACS and non ACS.
Cohort study.
The study was conducted in the emergency department and cardiac care units of the Aga Khan University in 2006-07.
A total of 202 patients, who presented to the emergency room with chest pain, were given an initial ECG and troponin check. Patients were assigned to initial ACS and non-ACS groups by the cardiology resident. After cardiac workup, patients were assigned to final ACS/final non ACS group. They were followed for outcome after 30 days of initial presentation. Sensitivity and specificity, if initial workup was determined, keeping final assessment after cardiac workup as the gold standard.
Out of the 202 patients, 61.9% were males. Their mean age was 54.05+13 years. Sixty eight percent were placed in the initial ACS group and 30.7% were placed in the initial non ACS group. After workup, 36% were placed in the final ACS group and 28.7% in the final non-ACS group and 35% were undecided. The sensitivity of initial assessment of ACS by the cardiology resident was 100%. However, the specificity was 54.2%. In the 30-day outcome, one patient (1.3%) died in the ACS group due to myocardial ischemia while no patient died from the non ACS group.
Initial assessment about ACS by cardiology resident based on character of chest pain, ECG and troponin I is highly sensitive. However, the specificity is low.
确定急诊室心内科住院医师对急性胸痛患者急性冠状动脉综合征(ACS)诊断的初始临床评估的敏感性和特异性,并评估ACS和非ACS患者的30天预后。
队列研究。
2006 - 2007年在阿迦汗大学急诊科和心脏监护病房进行该研究。
共有202例因胸痛就诊于急诊室的患者接受了初始心电图和肌钙蛋白检查。心内科住院医师将患者分为初始ACS组和非ACS组。经过心脏检查后,将患者分为最终ACS/最终非ACS组。在初次就诊30天后对他们进行预后随访。以心脏检查后的最终评估为金标准,确定初始检查的敏感性和特异性。
202例患者中,61.9%为男性。他们的平均年龄为54.05 + 13岁。68%的患者被归入初始ACS组,30.7%的患者被归入初始非ACS组。经过检查后,36%的患者被归入最终ACS组,28.7%的患者被归入最终非ACS组,35%的患者情况未明确。心内科住院医师对ACS初始评估的敏感性为100%。然而,特异性为54.2%。在30天预后中,ACS组有1例患者(1.3%)因心肌缺血死亡,而非ACS组无患者死亡。
心内科住院医师基于胸痛特征、心电图和肌钙蛋白I对ACS进行的初始评估具有高度敏感性。然而,特异性较低。