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非裔美国人的抗高血压治疗:来自市中心门诊诊所的发现。

Antihypertensive therapy in African Americans: findings from an inner-city ambulatory clinic.

机构信息

Department of Medicine, Yale University School of Medicine (Bridgeport Hospital), Bridgeport, CT, USA.

出版信息

J Clin Hypertens (Greenwich). 2010 Mar;12(3):187-92. doi: 10.1111/j.1751-7176.2009.00248.x.

Abstract

African Americans bear a greater burden of hypertension. Understanding prevailing epidemiologic patterns can facilitate the implementation and successful outcome of community programs. The authors assessed practice patterns of antihypertensive drug utilization and blood pressure (BP) control in a predominantly African American population in Brooklyn, NY, from January 1 to January 31, 2008. A total of 416 (53.1%) had hypertension, with a mean age of 61 years, and 267 (64%) were women. In general, 212 (50.9%) were at goal BP and 59.9% of those at goal were taking at least 2 drugs. Patient age correlated with the number of drugs used (r=0.14; P=.004). Patients taking beta-blockers and calcium channel blockers were older: 63.6 vs 60.1 years (P=.01) and 62.7 vs 60.3 years (P=.07), respectively. The pattern of antihypertensive use was as follows: angiotensin-converting enzyme inhibitors, 194 (46.6%); calcium channel blockers, 162 (38.9%); diuretics, 162 (38.9%); beta-blockers, 133(32%); and angiotensin receptor blockers, 93 (22.4%). The findings of age associated with the class of medications used and a predominance of angiotensin-converting enzyme inhibitors usage highlight possible gaps in appropriateness of antihypertensive therapy. The application of age-appropriate race-based antihypertensive therapy might improve BP control rates. These results strengthen arguments for investing in community-based programs to overcome possible provider-related and local health system barriers to achieving BP control goals.

摘要

非裔美国人承受着更大的高血压负担。了解流行的流行病学模式可以促进社区项目的实施和成功。作者评估了 2008 年 1 月 1 日至 1 月 31 日在纽约布鲁克林的一个以非裔美国人为主的人群中抗高血压药物使用和血压(BP)控制的实践模式。共有 416 人(53.1%)患有高血压,平均年龄为 61 岁,267 人(64%)为女性。一般来说,212 人(50.9%)的血压达到目标,在达到目标的人中,有 59.9%的人服用至少 2 种药物。患者年龄与使用药物的数量相关(r=0.14;P=.004)。服用β受体阻滞剂和钙通道阻滞剂的患者年龄较大:63.6 岁比 60.1 岁(P=.01)和 62.7 岁比 60.3 岁(P=.07)。抗高血压药物的使用模式如下:血管紧张素转换酶抑制剂,194 例(46.6%);钙通道阻滞剂,162 例(38.9%);利尿剂,162 例(38.9%);β受体阻滞剂,133 例(32%);和血管紧张素受体阻滞剂,93 例(22.4%)。年龄与使用药物类别的关系以及血管紧张素转换酶抑制剂使用的优势突出了降压治疗的适当性方面可能存在差距。应用适合年龄的基于种族的降压治疗可能会提高血压控制率。这些结果为投资于基于社区的项目以克服实现血压控制目标的可能与提供者相关和当地卫生系统障碍提供了依据。

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