[丙泊酚给药期间麻醉深度的反馈控制。以脑电双频指数作为控制变量]
[Feedback control of depth of anesthesia during propofol administration. Bispectral index as the controlled variable].
作者信息
Janda M, Bajorat J, Simanski O, Kähler R, Pohl B, Nöldge-Schomburg G F E, Hofmockel R
机构信息
Klinik und Poliklinik für Anästhesiologie und Intensivtherapie, Universität Rostock, Schillingallee 35, 18055 Rostock, Deutschland.
出版信息
Anaesthesist. 2010 Jul;59(7):621-7. doi: 10.1007/s00101-010-1731-9.
BACKGROUND
The objective of this study was to evaluate the performance of a new system for closed-loop control of propofol administration using the bispectral index (BIS) under total intravenous anesthesia in the index values of middle-to-deep depth of anaesthesia.
METHODS
In this study 20 adult patients anesthetized with propofol and remifentanil were investigated. The propofol infusion was carried out using a fuzzy-PD+I controller with a target BIS value of 40.
RESULTS
Closed-loop control was able to provide maintenance of anesthesia and adequate operating conditions for all patients. The following quality control criteria were calculated: median performance error (MDPE; 0.16%, SD +/-1.4%), median absolute performance error (MDAPE; 6.9%, SD +/-2.8%) and wobble (6.8%, SD +/-2.5%).
CONCLUSION
The present study showed the clinical feasibility of the controller compared to existing devices regarding a high level of quality criteria of a model with an implemented fuzzy-PD+I structure controlling depth of hypnosis.
背景
本研究的目的是评估一种在全静脉麻醉下使用脑电双频指数（BIS）对丙泊酚给药进行闭环控制的新系统在中深度麻醉指数值方面的性能。
方法
本研究对20例接受丙泊酚和瑞芬太尼麻醉的成年患者进行了调查。使用模糊-PD+I控制器进行丙泊酚输注，目标BIS值为40。
结果
闭环控制能够为所有患者维持麻醉并提供足够的手术条件。计算了以下质量控制标准：中位性能误差（MDPE；0.16%，标准差±1.4%）、中位绝对性能误差（MDAPE；6.9%，标准差±2.8%）和摆动（6.8%，标准差±2.5%）。
结论
本研究表明，与现有设备相比，该控制器在具有模糊-PD+I结构的模型控制催眠深度的高质量标准方面具有临床可行性。
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