应激相关生活质量结局在儿童癌症和脑肿瘤幸存者父母中的表现：一项病例对照研究。
Stress-mediated quality of life outcomes in parents of childhood cancer and brain tumor survivors: a case-control study.
机构信息
Department of Population Health Sciences, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53792-4108, USA.
出版信息
Qual Life Res. 2010 Sep;19(7):995-1005. doi: 10.1007/s11136-010-9666-9. Epub 2010 May 15.
PURPOSE
To determine if caring for a child with cancer or a brain tumor affects parental health and mental health and if and to what extent stress mediates the relationship between case status and parental quality of life.
METHODS
In person interviewer-assisted surveys were administered to 74 case dyads (children diagnosed with cancer or a brain tumor and their parents) and 129 control dyads (children without health problems and their parents from a community sample) to assess health-related quality of life and perceived levels of stress.
RESULTS
Parents of children with cancer or a brain tumor had significantly worse health-related quality of life, including worse overall mental health. Overall physical health was no different between cases and controls. Staged multivariate analysis revealed that worse health-related quality of life is completely mediated by perceived stress in these parents.
CONCLUSIONS
The experience of caring for a child with cancer is not in itself related to poor quality of life, but is related to an increased level of stress that may adversely impact parental mental health and quality of life.
目的
确定照顾癌症或脑肿瘤患儿是否会影响父母的健康和心理健康，以及压力是否以及在何种程度上调节病例状况与父母生活质量之间的关系。
方法
对 74 例病例对（患有癌症或脑肿瘤的儿童及其父母）和 129 例对照组（来自社区样本的无健康问题的儿童及其父母）进行了面访式调查，以评估与健康相关的生活质量和感知压力水平。
结果
癌症或脑肿瘤患儿的父母生活质量明显较差，包括整体心理健康状况较差。病例组和对照组的整体身体健康状况没有差异。多阶段多元分析显示，这些父母的生活质量较差完全是由感知压力引起的。
结论
照顾癌症患儿的经历本身与生活质量差无关，但与压力水平升高有关，这可能对父母的心理健康和生活质量产生不利影响。
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