Institute for Health, Health Care Policy and Aging Research, Rutgers, The State University of New Jersey, New Brunswick, NJ 08901, USA.
Int Psychogeriatr. 2010 Nov;22(7):1161-71. doi: 10.1017/S1041610210000578. Epub 2010 May 18.
Understanding the prevalence, incidence and cofactors of depression among long-term elderly nursing home (LTNH) residents domiciled for eight months or more may help optimize depression treatment in this vulnerable group. We quantified first year depression in American LTNH residents and the associations between depression and resident/facility characteristics.
Data were obtained from the Minimum Data Set and Online Survey Certification and Reporting for 634,060 LTNH residents admitted from 1999 to 2005 in 4,216 facilities. Depression first diagnosed at admission and at subsequent quarterly intervals through the first year of stay was examined. Logistic regressions modeled correlates of newly identified depression in each time-period.
Recorded depression at admission and during the first year increased from 1999 to 2005. By 2005, 54.4% of LTNH residents had depression diagnosed over the first year; 32.8% at admission and a further 21.6% later during the first year. Antidepressant use was reported prior to depression diagnosis for 48% of those first identified depressed after admission. Men, non-Hispanic blacks, never married, and severely-cognitively impaired LTNH residents were less often identified with depression, particularly at admission. Pain and physical comorbidity were positively associated with depression identified throughout the first year. Prior institutionalization was associated with depression at admission, but not new depression after admission. Facility characteristics had weaker associations with depression.
High depression rates at admission and during the first year indicate a need to monitor and treat large numbers of American LTNH residents for depression. Reduced associations between demographics and depression as stays progress suggest other factors have increased roles in depression etiology.
了解长期居住在养老院(LTNH)且居住时间达到或超过 8 个月的老年人的抑郁发生率、患病率和相关因素,有助于优化这一弱势群体的抑郁治疗。本研究量化了美国 LTNH 居民在入住第一年的抑郁情况,并分析了抑郁与居民/机构特征之间的相关性。
本研究数据来自 1999 年至 2005 年间,4216 家机构中 634060 名 LTNH 居民的最低数据组和在线调查认证与报告。通过对首次入院和随后每季度的调查,评估了入住第一年期间首次确诊的抑郁情况。采用逻辑回归模型分析了每个时间段新确诊的抑郁相关因素。
记录显示,入院时和入住第一年期间的抑郁发生率呈上升趋势。到 2005 年,54.4%的 LTNH 居民在第一年期间被诊断出患有抑郁症;32.8%在入院时,另外 21.6%在入住后的第一年。在首次入院后被诊断为抑郁的人群中,有 48%在确诊前曾使用过抗抑郁药物。男性、非裔美国人、未婚和严重认知障碍的 LTNH 居民较少被诊断出患有抑郁症,尤其是在入院时。疼痛和身体合并症与整个第一年的抑郁诊断呈正相关。入院前的机构化与入院时的抑郁相关,但与入院后的新发抑郁无关。机构特征与抑郁的相关性较弱。
较高的入院时和第一年的抑郁发生率表明,需要对大量的美国 LTNH 居民进行抑郁监测和治疗。随着入住时间的延长,人口统计学因素与抑郁的相关性降低,这表明其他因素在抑郁病因学中发挥了更大的作用。