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[耳部肿瘤放射治疗的方法学方面]

[Methodological aspects of radiotherapy in the treatment of ear neoplasms].

作者信息

Antoniv V F, Stiop L D, Kuznetsov O G

出版信息

Vestn Otorinolaringol. 1991 Mar-Apr(2):15-8.

PMID:2048244
Abstract

During 1978 to 1988, 35 patients with ear carcinoma (22 men and 13 women, aged 30 to 74 years) were treated. In 62% cases the tumor originated from the external acoustic meatus, in 30% cases--from the postoperative cavity (in patients operated on for chronic inflammation), and in 8% cases it was a primary tumor of the concha auriculae. 77% of the patients developed the III or IV stage of disease and 71% of patients had squamous cell carcinoma. Six patients underwent radiation therapy (Group 1), nine-radiation therapy and subsequent surgery within 14 to 30 days after exposure (Group 2), and twenty patients were exposed first to surgery and then to postoperative radiation therapy (Group 3). All the patients were followed up for at least one year and eight of them--for not less than 5 years. At the present time survivors make 37% of all the patients. In the study only routine dose fractionation was used. Regional metastatic areas were also exposed to irradiation. It is stressed that efforts are needed to increase the local effect of ear tumor therapy. Indications and contraindications for radiation therapy are presented and protocols of radiation therapy are described.

摘要

1978年至1988年期间,对35例耳部癌患者(22例男性和13例女性,年龄30至74岁)进行了治疗。62%的病例中肿瘤起源于外耳道,30%的病例——起源于术后腔隙(慢性炎症手术患者),8%的病例为耳甲原发性肿瘤。77%的患者疾病发展至III或IV期,71%的患者为鳞状细胞癌。6例患者接受放射治疗(第1组),9例患者先接受放射治疗,然后在照射后14至30天内接受手术(第2组),20例患者先接受手术,然后接受术后放射治疗(第3组)。所有患者均随访至少1年,其中8例——随访不少于5年。目前,幸存者占所有患者的37%。该研究仅采用常规剂量分割。区域转移部位也接受了照射。强调需要努力提高耳部肿瘤治疗的局部效果。介绍了放射治疗的适应证和禁忌证,并描述了放射治疗方案。

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