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多发伤后骨科损伤晚期临床结局的预测因素

Predictors of late clinical outcome following orthopedic injuries after multiple trauma.

作者信息

Pape Hans-Christoph, Probst Christian, Lohse Ralf, Zelle Boris A, Panzica Martin, Stalp Michael, Steel Jennifer L, Duhme Heinrich M, Pfeifer Roman, Krettek Christian, Sittaro Nicola-Alexander

机构信息

Department of Orthopaedic Trauma, University of Aachen Medical Center, Aachen, Germany.

出版信息

J Trauma. 2010 Nov;69(5):1243-51. doi: 10.1097/TA.0b013e3181ce1fa1.

Abstract

BACKGROUND

The long-term clinical status of surviving patients with multiple injuries has not been well described. The aim of this study was to evaluate whether certain injury patterns predispose a patient to a poor clinical outcome 10 or more years after multiple injuries.

METHODS

Patients who were treated at a level I trauma center at least 10 years before participation in this study were reinvited for a follow-up physical examination. Clinical outcome included the assessment of pain, gait, and various outcome scores (Short-Form [SF]-12, Lysholm, Merle D'Aubigne) were also used to measure outcome.

STATISTICS

Binary logistic regression was used to test predictors of physical and psychosocial outcomes 10 years or longer after trauma. Differences between the types of injury and outcomes were assessed using Mann-Whitney and Kruskal Wallis tests.

RESULTS

Of 1,034, 637 patients (62%) participated in this study. Predictors of poor physical and psychosocial functioning using a clinical outcome score at 10 or more years follow-up included lower extremity amputation (odds ratio = 15.08; 95% confidence interval = 1.87-121.61) and a higher Abbreviated Injury Scale (AIS) spine score (SF-12 Mental subscale [odds ratio = 0.78; 95% confidence interval = 0.64-0.96]). Other factors associated with worse outcome scores were presence of two or more articular injuries, lower extremity injuries, and a combination of shaft and articular injuries.

CONCLUSION

If patients survived, traumatic lower extremity amputation and a high initial maximum AIS (MAIS) spine score was the only predictive parameter for an increased odds of adverse clinical outcomes late after trauma. Injuries associated with these outcomes should be the focus of attention regarding injury prevention and priority in care.

摘要

背景

多处受伤存活患者的长期临床状况尚未得到充分描述。本研究的目的是评估某些损伤模式是否会使患者在多处受伤10年或更长时间后出现不良临床结局。

方法

在参与本研究至少10年前在一级创伤中心接受治疗的患者被再次邀请进行随访体格检查。临床结局包括疼痛、步态评估,还使用了各种结局评分(简短健康调查[SF]-12、Lysholm评分、Merle D'Aubigne评分)来衡量结局。

统计学方法

采用二元逻辑回归检验创伤后10年或更长时间身体和心理社会结局的预测因素。使用Mann-Whitney检验和Kruskal Wallis检验评估损伤类型与结局之间的差异。

结果

1034名患者中,637名(62%)参与了本研究。在10年或更长时间的随访中,使用临床结局评分预测身体和心理社会功能不良的因素包括下肢截肢(比值比=15.08;95%置信区间=1.87-121.61)和较高的简明损伤定级标准(AIS)脊柱评分(SF-12心理分量表[比值比=0.78;95%置信区间=0.64-0.96])。与较差结局评分相关的其他因素包括存在两处或更多关节损伤、下肢损伤以及骨干和关节损伤的组合。

结论

如果患者存活,创伤性下肢截肢和高初始最大AIS(MAIS)脊柱评分是创伤后期不良临床结局几率增加的唯一预测参数。与这些结局相关的损伤应成为预防损伤关注的重点和护理的优先事项。

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