钯纳米粒子催化的苄基卤化物的 Hiyama 偶联反应。

Palladium nanoparticle catalyzed Hiyama coupling reaction of benzyl halides.

机构信息

Department of Organic Chemistry, Indian Association for the Cultivation of Science, Kolkata 700032.

出版信息

J Org Chem. 2010 Jun 18;75(12):4296-9. doi: 10.1021/jo1003373.

PMID:20491503

Abstract

An efficient Hiyama coupling reaction between benzylic halide and aryltrialkoxysilane using Pd nanoparticles has been developed. This procedure accommodates various functional groups to yield a diverse range of diarylmethanes which are ubiquitous units of natural products and pharmaceuticals.

摘要

发展了一种钯纳米粒子催化的苄卤和芳基三烷氧基硅烷的高效 Hiyama 偶联反应。该方法可兼容各种官能团，生成各种二芳基甲烷，这些都是天然产物和药物中常见的结构单元。