Department of Surgical Sciences, Catholic University of the Sacred Heart, Rome, Italy.
Eur Rev Med Pharmacol Sci. 2010 Apr;14(4):327-33.
Small intestinal neoplasms are uncommon cancers. Benign small intestinal tumors (e.g., leiomyoma, lipoma, hamartoma, or desmoid tumor) usually are asymptomatic but may present with complications. Primary malignancies of the small intestine, including adenocarcinoma, leiomyosarcoma, carcinoid, and lymphoma, are often symptomatic and may present with intestinal obstruction, jaundice, bleeding, or pain. Metastatic neoplasms may involve the small intestine via contiguous spread, peritoneal metastases or hematogenous metastases. Because the small intestine is relatively inaccessible to routine endoscopy, diagnosis of small intestinal neoplasms is often delayed for months after onset of symptoms. During last years the increase of small bowel endoscopy and other diagnostic tools allow earlier non-operative diagnosis. Even though radical resection of small bowel cancer plays an important role, the 5 yr overall survival remains low.
小肠肿瘤并不常见。良性小肠肿瘤(如平滑肌瘤、脂肪瘤、错构瘤或硬纤维瘤)通常无症状,但可能会出现并发症。小肠原发性恶性肿瘤,包括腺癌、平滑肌肉瘤、类癌和淋巴瘤,通常有症状,并可能出现肠梗阻、黄疸、出血或疼痛。转移性肿瘤可通过连续播散、腹膜转移或血行转移累及小肠。由于小肠相对难以通过常规内镜检查,因此小肠肿瘤的诊断通常在症状出现后数月才得以确诊。近年来,小肠内镜和其他诊断工具的增加使得非手术诊断得以更早实现。尽管根治性切除小肠癌发挥着重要作用,但 5 年总生存率仍然较低。